Heterocyclic Chemistry Flashcards
Write down mechanisms that explain the selectivity of activated benzene rings
Write down mechanisms that explain the selectivity of deactivated benzene rings
Using curly arrows, show the reactivity of 5 member heterocycles to electrophillic substitution
Draw out the bromination of a 5 member heterocycle and explain why although you get a dibrominated cycle, it ends up becoming a singly brominated cycle.
Write down the chichibabin reaction
Write down reaction to creat n-oxides from pyridine and how to eliminate it after reactions have occured
Write down a feist benary synthesis to synthesise a furan
Write down the fischer synthesis to synthesise an indole
Write down the hantzsch synthesis to synthesise a pyridine
Write down the mechanism for this reaction
Write down the mechanism for this reaction
Why is it that indoles only rect at the 2 position when it should be the 3 position?
Write down the mechanism to generate a nitrate cation
This is sulphuric acid and nitric acid
Write down the mechanism for paal knorr synthesis of furans
How do you get pyrrols and thiophenes
Pyrroles form if you react the diketone with amine
Thiophenes are formed if you use P4S10 or lawson’s reagent
What are the coniditons required for SnAr to occur?
Requires a leaving group and for an R group para to the subtitution site which is EWG in order to stabilise the charge
