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Theory > HES > Flashcards

HES Flashcards

1
Q

Definition of hes

A

Blood eosinophilia >1500 on 2 diff occasions >1month
Tissue ->20% on bm
Tissue infiltration

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2
Q

Variants 3 of hes

A

Myeloproliferative
Lymphocytic
Idiopathic

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3
Q

Myeloproliferative what is positive

A

Positive pdgfra

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4
Q

Lymphocytic what is increased

A

Increased il- 5

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5
Q

Labs

A 
Blood eosinophilia >1500
Ige
Hypergammaglobulinemia
Esr>15
Bal eosinophilia
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6
Q

Rx

A

Imatinib- tk inhibitors in pdgera pos
Plus cs.

Cs- pdgera neg

Ifn alpha- cs resistant
Mepolizumab- il-5

Bm tx

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Theory (29 decks)

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