Heritable Thrombocytophilias TOG 2011 Thrombophilia testing in women with adverse pregnancy outcomes 2017

Question 1

What proportion of the population has an inherited thrombophila?

Answer 1

11%

Question 2

Most common heritable thrombophiila?

Answer 2

Factor V leiden

Question 3

List major heritable thrombophilias

Answer 3

Factor V leiden
Prothrombin mutation
Protein S deficiency
Protein C deficiency
Antithrombin deficiency
Factor XIII mutation

Question 4

List acquire thrombophilias

Answer 4

Lupus anticoagulant
ß2-glycoprotein antibodies
Anticardiolipin antibodies

Question 5

When to test from thrombophilia

Answer 5

Hx unprovoked venous thrombosis
Thombosis in pregnancy to COCP
Minor provoking factor e.g. travel
1st degree family, unprovoked thrombosis/related to pregnancy/COCO/minor RD

Question 6

How long after even should wait to test for protein C/S/antithrombin deficiency?

Answer 6

4 weeks after event

Question 7

For how long after DVT should wear compression stockings>?

Answer 7

2 years

Question 8

Highest risk thrombophilia for VTE in pregnancy

Answer 8

Antithrombin