Heredity Flashcards
What are the two things that Gregor Mendel is credited with the discovery of?
Segregation and independent assortment
Segregation
Refers to the segregation of alleles in gametes
Independent Assortment
Alleles assort independently; the migration of one allele does not affect the migration of another
What are different generations called?
P (paternal), F1(filial), F2 (in order)
Monohybrid cross
A genetic cross investigating only one trait
Dihybrid cross
A genetic cross investigating two traits
Complete dominance
When a dominant allele causes a trait to be expressed completely over a recessive one: they don’t share
Test cross
When one mates an unknown-genotype plant with another known-genotype plant in order to determine its genotype
Incomplete dominance
Instead of complete dominance, the traits kind of mix (example: snapdragons with one pink and one white allele are pink)
Codominance
Both alleles are expressed, but they don’t mix. Think a piebald horse.
Explain why blood transfusions aren’t universal
There are six different alleles mixes for the different blood types (i, IA, IB), which indicate which (if any) sugars they have attached to the person’s cells. If the person gets a kind of blood with sugars that don’t match, their immune system will attack it, leading to agglutination and possible death.
Polygenic Inheritance
The interaction of many genes to create one phenotype. . This is often expressed a a continuous variation.
Linked genes
Genes that are physically located close to each other and therefore do not segregate separately, and are usually inherited together. A linkage map is one made by evaluating the recombination frequencies to theorize about which genes are close.
Autosome
chromosomes that aren’t sex chromosomes
Sex limited traits
Traits that are limited by one sex chromosome (it has sections that code for how active regions on autosomes will be), such as male baldness
Sex linked traits
Traits that reside on a sex chromosome. Usually X chromosome, since Y chromosome is small.
X-inactivation
When, in females, one X chromosomes remains coiled in a Barr body as opposed to unfurling into chromatin. This happens independently in each cell, so not all cells in a female body are functionally the same.
Nondisjunction
The failure of one or more chromosome pairs/ chromatids of a single chromosome to properly move to opposite poles during meiosis or mitosis.
Give examples of nondisjunction
- During meiosis, the failure of two homologous chromosomes to separate (trisomy 21)
- During meiosis, one cell getting confused and its decedents being confused too
- Too many gametes, causing polyploidy in a zygote
Point mutation
When a different nucleotide takes the place of the intended one (substitution), one is deleted (deletion), or one is inserted (insertion)
Aneuploidy
A genome with extra or missing chromosomes (trisomy 21(down syndrome) Turner syndrome)
Chromosomal aberrations
When chromosome segments are changed (duplicated or squashed onto another chromosome).
Non-Nuclear Inheritence
Mitochondria and chloroplasts carry their own DNA and reproduce by themselves (this is endosymbiotic theory that mitochondria and chloroplasts used to be other organisms that lived with us)