Hepatomegaly and Hepatsplenomegaly Flashcards
1
Q
Hepatomegaly
A
Common causes
CIRRHOSIS - If early disease later liver decreases in size. Assoc w non-tender firm liver
MALIGNANCY - Metastatic spread or primary hepatoma. Assoc w hard, irregular liver edge
RIGHT HEART FAILURE - Firm, smooth, tender liver edge. May be pulsatile
Other Causes:
- Viral hepatitis
- Glandular fever
- Malaria
- Abscess - Pyogenic, Amoebic
- Hydatid disease
- Haematological malignancies
- Haemochromatosis
- PBC
- Sarcoidosis
- Amyloidosis
2
Q
Hepatosplenomegaly
A
Causes:
- Chronic liver disease w portal HTN
- Infections: Glandular fever, Malaria, Hepatitis
- Lymphoproliferative disorders
- Myeloproliferative disorders eg CML
- Amyloidosis
NB Infective endocarditis causes an ISOLATED splenomegaly
