Hepato 2 - Colangite Biliar Primaria Flashcards

1
Q

Conceito

A

Inflamacao auto imune dos ductos biliares, sem acometer a via biliar

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2
Q

Epidemio

A

Mulheres 40-60a

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3
Q

Fisiopato

A

Elevacao de IgM -> Lesao imune em ductos biliares -> estenose + acumulo de bile -> toxicidade hepatica -> lesao hepatica e cirrose

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4
Q

Clinica

A
Assintomatica
Fadiga
Prurido
Xantelasma
Ictericia
Osteopenia
Hiperpigmentacao cutanea
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5
Q

Exames complementares

A

Eleva FA e Hipercolesterolemia

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6
Q

Associacao

A

Sjogren e hashimoto

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7
Q

Diag

A

Anticorpo anti-mitocondria (AMA)

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8
Q

TTO

A
Acido ursodesoxicolico (sal biliar sintetico, que faz com que o figado para de produzir bile )
Transplante em ultimos casos
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9
Q

Diag diferencial

A

Colangite esclerosante primaria e hepatite auto imune

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