HEPATITIS VIRUSES Flashcards
infectious/non chronic hepatitis
hepatitis A virus
primary transmission of hepa A virus
contaminated food/water/household contact
hepa A endemic countries
bangladesh, india, nepal, pakistan
1 endemic country for Hepa A
india
tests for HAV
HAV RNA through NAAT in stool/blood, IgG/IgM ELISA
Pleomorphic, incomplete/partial dsDNA that replicates through RNA intermediate
hepadnaviridae
transmission of Hepatitis B
percutaneous inoculation, perinatal, sexual
incubation period of HBV
1-3 months
coinfection of HBV
HDV
Mild, acute or chronic, complications leads to liver cirrhosis and hepatocellular carcinoma
HBV
Best indication of viral replication and high state infectivity
HBV DNA
identification of virus
HbsAg
most reliable marker for HBV infection
HbsAg
high infectivity, chronic carrier state
HbeAg
acute infection
Anti-HBc IgM
chronic infection
Anti-HBc IgG
convalescence, vaccination, developed immunity
Anti-HBsAg
Liver Parenchymal damage
ALT, AST
deficient RNA virus that needs HBV to replicate in cells
HDV
Hepatitis, hepatocellular carcinoma
Hepatitis C virus
screening for HCV
Anti-HCV EIA or NAAT
transmission of HCV
through blood exchange
HEV disease
Acute and generally self-limiting with liver enlargement but no further disease progression
HEV high fatality in _____
pregnant woman at 3rd trimester
