Hepatitis E Flashcards

1
Q

what is the definition of hep E?

A

Hepatitis E is an illness of the liver caused by hepatitis E virus ( HEV ), a virus which can infect both animals and humans. HEV infection usually produces a mild disease, hepatitis E. However, disease symptoms can vary from no apparent symptoms to liver failure. Hepeviridae family of single stranded RNA virus

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2
Q

how can hep E be prevented?

A

Improved hygiene and drinking clean water are the key factors in prevention.

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3
Q

how is hep E diagnosed?

A

Definitive diagnosis of hepatitis E infection is usually based on the detection of specific anti-HEV immunoglobulin M (IgM) antibodies to the virus in a person’s blood; this is usually adequate in areas where the disease is common. Rapid tests are available for field use.
Additional tests include reverse transcriptase polymerase chain reaction (RT-PCR) to detect the hepatitis E virus RNA in blood and stool.

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4
Q

what is the epidemiology of hep E?

A

Hepatitis E is found worldwide, but the disease is most common in East and South Asia.

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5
Q

what are the symptoms of hep E?

A

an initial phase of mild fever, reduced appetite (anorexia), nausea and vomiting lasting for a few days;
abdominal pain, itching , skin rash, or joint pain;
jaundice (yellow colour of the skin), dark urine and pale stools; and
a slightly enlarged, tender liver (hepatomegaly).

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6
Q

how is hep E treated?

A

There is no specific treatment capable of altering the course of acute hepatitis E. As the disease is usually self-limiting, hospitalization is generally not required. Most important is the avoidance of unnecessary medications. Acetaminophen, paracetamol and medication against vomiting should be used sparingly or avoided.

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