Hepatitis A Flashcards
self-limited disease, less fatal/milder, does not
result to chronic infection
Acute Viral Hepatitis
T/F. Vaccine is available
True
Hepa A Virology (PINS)
Picornaviridae Family
Icosahedral
Non-enveloped
Single-stranded RNA
other name for Hepa A
Enterovirus 72
Most common cause of hepatitis
Hepa A
Has an abrupt onset (______ hepatitis) HAV
short incubation
Incubation Period
15-50 days
Average
20 days
Hepa A MOT
fecal-oral
blood transfusion
sheds off in the intestine; antigen detection in the stool sample is recommended
0-15 days
antibodies starts to be
produced IgM -> IgG
2nd week of infection
Icterus
jaundice, ↑ bilirubin
↑ liver enzyme levels
ALT/SGPT
Acute Infection
(+) IgM
Old infection
(+) IgG
Incubation/ NO infection
(-) IgM, IgG
Hepa A Detection
Indirect ELISA
RIA