Hepatitis

Question 1

Peak titers of ______ occur during the first week of clinical disease and disappear within 3-6 months

Answer 1

IgM

Question 2

Titers of ______ rise after one month of the disease an may persist for years

Answer 2

IgG

Question 3

_____ in the absence of ____ indicates previous exposure to hep A virus, non infectivity an immunity

Answer 3

IgG without IgM

Question 4

Hep A has an incubation time of __________

Answer 4

4 weeks

Question 5

Detect _______ during acute illness when serum aminotransferase is high and fecal shedding is still occuring

Answer 5

anti-HAV

Question 6

Early antibody response is _____ - for 3 months

Answer 6

IgM

Question 7

During recovery _______ becomes dominant

Answer 7

anti-HAV IgG

Question 8

To make an early diagnosis use early __________

Answer 8

IgM anti-HAV

Question 9

After illness, __________ remains detectable indefinitely, pts that establish this are immune to reinfection

Answer 9

anti-HAV IgG

Question 10

First virologic marker of Hep B

Answer 10

HBsAg

Question 11

_________remains elevated during the entire time of acute hep B and beyond

Answer 11

HBsAg

Question 12

Earliest marker of Hep B

Answer 12

HBsAg

Question 13

_________is a core antibody- reflects infection in the past but is not useful by itself

Answer 13

Anti-HBc

Question 14

_________ appears during incubation period, shortly after the detection of HBsAg

Answer 14

HBeAg

Question 15

_________ indicates viral infectivity

Answer 15

HBeAg

Question 16

Persistence of _________beyond 3 months indicates and increased likelihood of chronic hep B

Answer 16

HBeAg

Question 17

__________signifys diminished viral replication and decreased infectivity

Answer 17

anti-HBe

Question 18

The presence of ________ is the most specific and sensitive to early detection of hep B

Answer 18

HBV-DNA

Question 19

Serum aminotransferase are ______in hep B

Answer 19

higher

Question 20

___________positive mothers may transmit HBV at delivery

Answer 20

HBsAg

Question 21

When to admit with Hep B

Answer 21

encephalopathy
liver failure
unable to maintain hydration

Question 22

______________ indicates that you either have hep C now or you have had it at some point

Answer 22

Anti-HCV

Question 23

Treatment with ____________ for 6-24 decreases the risk of chronic hep C

Answer 23

peginterferon

Question 24

_____________ may be added if HCV RNA is not cleared after 3 months of peginterferon

Answer 24

ribaviran

Question 25

HDV causes hep D only in the presence of __________

Answer 25

HBsAg

Question 26

MC cause of acute liver failure

Answer 26

acetaminophen tox