Hepatic Phys And Anesthesia Flashcards
What is not a apart of MELD score?
Serum albumin
Which is a more objective score Child-Pugh ?
Meld because it does not look at things that are subjective such as encephalopathy or as cities
What are the components of the MELD score?
Serum creatinine
Bilirubin
INR
What enzyme is messed up in Gilbert syndrome?
Bilirubin glucoronyltransferase
What happens in Gilbert with massive blood transfusion
Postoperative jaundice due to overwhelming of the enzyme
What does glucagon do to hepatic blood flow?
Increases it along with D1 and Beta 2 receptors in the hepatic artery
How much cardiac output does the liver receive.
25%
Which vessel to the liver exhibits autoregulation?
Hepatic artery
What happens to the hepatic arterial flow when portal vein decreases?
It will increase due to accumulation of adenosine which causes vasodilation via the A2 receptors
What agents decrease hepatic blood flow?
Beta blockers due to the beta 2 in the hepatic artery
What do alpha receptors do to hepatic blood flow?
Decrease it
What does vasopressin do to hepatic blood flow?
Decreases it
What do D1 receptors do to hepatic blood flow?
Decrease it
What happens to hepatic blood flow in general anesthesia?
It decreases due to decreased cardiac output
Where is citrate metabolized?
The liver
What is citrate metabolized to?
Bicarbonate
What does glucagon do to hepatic blood flow?
Increases it along with D1 and Beta 2 receptors in the hepatic artery
How much cardiac output does the liver receive.
25%
Which vessel to the liver exhibits autoregulation?
Hepatic artery
What happens to the hepatic arterial flow when portal vein decreases?
It will increase due to accumulation of adenosine which causes vasodilation via the A2 receptors
What agents decrease hepatic blood flow?
Beta blockers due to the beta 2 in the hepatic artery
What do alpha receptors do to hepatic blood flow?
Decrease it
What does vasopressin do to hepatic blood flow?
Decreases it
What do D1 receptors do to hepatic blood flow?
Decrease it
