Hepatic Cases

Question 1

What is isolated elevated GGT significant for?

Answer 1

isolated elevation of GGT often points to alcohol consumption or certain drugs

Question 2

What pattern of liver injury would you expect in PBC?

Answer 2

cholestatic pattern of injury, most likely with elevated AMA

Question 3

What are symptoms of Gilbert’s syndrome?

Answer 3

common, benign condition with mild enzyme deficiency, during stress production of unconjugated bilirubin is not met by ability of the body to conjugate

Question 4

In what condition might you see portal inflammation, granulomas and ductopenia?

Answer 4

PBC

Question 5

In what condition may you find cholestasis, ductular proliferation, and feathery degeneration.

Answer 5

anything that causes a cholestatic pattern of damage: bile duct obstruction, cancer of the head to the pancreas obstructing the bile duct etc.

Question 6

What makes up Charcot’s triad and what is that diagnostic of?

Answer 6

fever, jaundice and RUQ pain is significant for acute ascending choleangitis