heparin and heparin derivatives Flashcards

1
Q

what does heparin enhance

A

antithrombin

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2
Q

lungs of cattle and intestines of pigs are sources of what drug

A

heparin

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3
Q

heparin is what type of anticoagulant

A

rapid acting anticoagulant

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4
Q

how is heparin administered

A

administered by Injection only

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5
Q

heparin is intermittent and continuous if given via

A

IV

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6
Q

where is heparin injected

A

subcutaneous (subQ)

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7
Q

heparin is the preferred anticoagulant during which conditions

A

pregnancy and when rapid anticoagulation is required

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8
Q

what drug is used for the conditions listed below
 Pulmonary embolism (PE)
 Stroke evolving
 Massive deep vein thrombosis (DVT)
 Open heart surgery
 Renal dialysis
 Low-dose therapy postoperatively
 Disseminated intravascular coagulation (DIC)
 Adjunct to thrombolytic therapy

A

heparin

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9
Q

what are the adverse effects of heparin

A

hemorrhage
heparin-induced thrombocytopenia (HIT)
hypersensitivity reactions

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10
Q

heparin is contraindicated for what conditions

A

thrombocytopenia; uncontrollable bleeding; during and immediately after surgery of the brain; eye; or spinal cord

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11
Q

what is the antidote for heparin overdose

A

protamine sulfate

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12
Q

what is used to monitor the anticoagulant response of heparin

A

activated partial thromboplastin time (aPTT)

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13
Q

what is the normal aPTT time ( activated partial thromboplastin time)

A

21 to 35 seconds

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