heparin and heparin derivatives Flashcards
what does heparin enhance
antithrombin
lungs of cattle and intestines of pigs are sources of what drug
heparin
heparin is what type of anticoagulant
rapid acting anticoagulant
how is heparin administered
administered by Injection only
heparin is intermittent and continuous if given via
IV
where is heparin injected
subcutaneous (subQ)
heparin is the preferred anticoagulant during which conditions
pregnancy and when rapid anticoagulation is required
what drug is used for the conditions listed below
Pulmonary embolism (PE)
Stroke evolving
Massive deep vein thrombosis (DVT)
Open heart surgery
Renal dialysis
Low-dose therapy postoperatively
Disseminated intravascular coagulation (DIC)
Adjunct to thrombolytic therapy
heparin
what are the adverse effects of heparin
hemorrhage
heparin-induced thrombocytopenia (HIT)
hypersensitivity reactions
heparin is contraindicated for what conditions
thrombocytopenia; uncontrollable bleeding; during and immediately after surgery of the brain; eye; or spinal cord
what is the antidote for heparin overdose
protamine sulfate
what is used to monitor the anticoagulant response of heparin
activated partial thromboplastin time (aPTT)
what is the normal aPTT time ( activated partial thromboplastin time)
21 to 35 seconds