direct thrombin inhibitors Flashcards

1
Q

dabigatrin and argatroban are drugs that are

A

direct thrombin inhibitors

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2
Q

dabigatran doesn’t require monitoring for what

A

doesn’t require monitoring for anticoagulation

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3
Q

are there little risk of adverse interactions when using dabigatran

A

yes

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4
Q

the same dose of dabigatran can be used by all patients regardless of

A

regardless of age and weight

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5
Q

what can be prescribed concurrently with dabigatran to prevent adverse effects of this drug

A

omeprazole

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6
Q

dabigatran can cause

A

bleeding and GI disturbances

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7
Q

true or false: there no specific antidote to reverse dabigatran related bleeding

A

true

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8
Q

argatroban is what type of anticoagulant

A

IV anticoagulant

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9
Q

what is the mechanism of action of argatroban

A

direct inhibition of thrombin

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10
Q

argatroban is indicated for prevention of DVT in patients undergoing what type of surgery

A

hip replacement surgery

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11
Q

argatroban is a prophylaxis and treatment of thrombosis in patients with

A

HIT

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