Heparin

Question 1

Uses

Answer 1

Treatment and prophylaxis of PE and Dvt

Used in coronary syndrome and MI

Coronary Artery occlusion

Thromboprophylaxis in medical and pregnancy sometimes

Patency of catethers

Question 2

Moa

Answer 2

Inhibits Xa. Enox and delta preferred for specific action.

This prevents prothrombin to. thrombin conversion reducing fibrogen to fibrin formation

Question 3

Side effects

Answer 3

Osteoporosis 
Alopexia 
Hyperlipidemia 
Rash hypersensitivity 
Bleeding 
Thrombocytopenia 
Hyperkalaemia

Question 4

Contraindications

Answer 4

Endocarditis
Elderly
Hypertension uncontrolled
Bleeding disorders and active peoticnulcer

Question 5

Drug interactions

Answer 5

Anti pallets such as aspirin and clopidregrel
Warfarin
Increase bleeding risk

Question 6

What can be given to reverse bleeding

Answer 6

Protamine

Question 7

How do you use

Answer 7

Iv in treatment and subcutaneously if prophylaxis measures
When inr 2-3 stop
Warfarin in dvt PE for 3
Months

Only
Refer if wells score is 2 or more unless pregnancy or been pregnant recently. Then do ultrasound and d dimer test within four hours.

Question 8

What can be done if emboli despite anti coagulation

Answer 8

Vena cava filter