Heparin Flashcards

1
Q

Generic name

A

Heparin

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2
Q

Trade Name

A

None

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3
Q

Class

A

Anticoagulant

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4
Q

Mechanism of Action

A

Blocks the conversion of prothrombin to thrombin and prevents the conversion of fibrinogen to fibrin

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5
Q

Indications

A

Acute myocardial infarction
Prophylaxis and treatment of thromboembolic disorders (DVT , PE)

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6
Q

Contraindications

A

Hypersensitivity
Active bleeding
Recent intracranial, intraspinal , eye surgery
Severe Hypertension

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7
Q

Side effects / adverse reactions

A

Hemorrhage
Pain
Bruising
Hematuria
Gi bleeding
Shock
Thrombocytopenia

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8
Q

Adult dose

A

Bolus 60 U/KG max 4,000 U IV/SQ
Infusion 12-15 U/KG HR max 1,000 U/HR

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9
Q

Pediatric dose

A

Not recommended

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10
Q

Drug Interactions

A

Chance of bleeding increases when used in conjunction with other anticoagulants

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11
Q

Duration of Action

A

Onset - immediate IV 20-60 minutes SQ
Peak - variable
Duration - 4-8 hours

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