Hep B Serologies

Question 1

HBsAGg

Answer 1

Signals an ongoing virus

Question 2

Anti-HBs

Answer 2

Signals recovery/ non infectivity/ immunity

Question 3

Anti-HBc

Answer 3

IgM: indicates acute Dx of Hep B
IgG: indicates no acute infection; persists indefinitely

Question 4

ABeAg

Answer 4

Indicates infectivity
(Persists longer than 3 mo= chronic infection)

Question 5

HBV DNA

Answer 5

Checks if chronic status is unknown

Question 6

A patient lab presents with:
HBsAg- negative
Anti-HBc- negative
Anti- HBs- negative

Whats their immune status?

Answer 6

Susceptible
(HBsAg= (-)—> no ongoing infection)
(Anti- HBc= (-)—> no ongoing or past infection)
(Anti- HBs = (-)—> no immunity)

Question 7

HBsAg= negative
Anti HBc= postive
Anti HCs= positive

Answer 7

No current infection
Immune due to natural infection

Question 8

HBsAg= negative
Anti- HBc= negative
Anti HBs= postive

Answer 8

Immune via vaccine

Question 9

HBsAg +
Anti-HBc +
IgM anti HBc +
Anti HBs= -

Answer 9

Acutely infected