Hep B and C Flashcards
What type of virus is Hep B?
DNA virus
How is Hep B transmitted?
B= bodily fluids and blood, vertical
What is the presentation of Hep B?
Asymptomatic Fatigue Itch, jaundice Anorexia Fever
What investigations are done for Hep B?
IgM IgG HBsAg HBcAg HBsAb Hep B virus DNA
What is IgM + and -?
+ in acute infection
- in chronic
What is IgG +?
Chronic infection
When is HBsAG seen?
Infected with Hep B
What is HBcAg seen?
Current or past infection
When is HBsAb seen?
Past infection or immunisation
What does Hep B virus DNA indicate?
Viral load
What is the management of Hep B?
Pegylated interferon
Antiviral
What is the prognosis for Hep B?
10% become chronic infection
What type of hepatitis is most prevalent in the UK?
Hep C
What type of virus is Hep C?
RNA virus
How is Hep C transmitted?
Circulation
What is the presentation of Hep C?
Asymptomatic Fatigue Jaundice, itch Anorexia Fever
What investigations are done for Hep C?
HCV antibody
Hep C RNA= viral load
What is the management for Hep C?
Direct acting antivirals
What is the prognosis for Hep C?
3/4 become chronic infection
What ar the complications of hepatitis?
Cirrhosis
hepatocellular carcinoma