Hemoglobin Production Flashcards
What erythrocytic stage does hemoglobin being produced?
Pronormoblast to reticulocytes
What organelle synthesize the Heme
Mitochondria
Composition of normal hemoglobin
Four heme molecules with nested four globin molecules
Heme components
Protoporphyrin IX ring with Iron in center
How much oxygen can combine to 1 heme molecule
1 Oxygen molecule
Globin portion components
Two pairs globin chain (2 alpha and 2 non alpha)
Hemoglobin functions
Transport of gases
The primary hemoglobin for gas transport
Oxyhemoglobin
What are the hemoglobin variants
- Methemoglobin
- Sulfhemoglobin
- Carboxyhemoglobin
Hemoglobin variant that leads to cyanosis
Sulfhemoglobin
Hgb variant containing Ferrous iron
Methemoglobin
Hgb variant that leads to irin binding carbon monoxide
Carboxyhemoglobin
Sulfhemoglobin is irreversible process. TRUE OR FALSE
True