Hemoglobin Production Flashcards

1
Q

What erythrocytic stage does hemoglobin being produced?

A

Pronormoblast to reticulocytes

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2
Q

What organelle synthesize the Heme

A

Mitochondria

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3
Q

Composition of normal hemoglobin

A

Four heme molecules with nested four globin molecules

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4
Q

Heme components

A

Protoporphyrin IX ring with Iron in center

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5
Q

How much oxygen can combine to 1 heme molecule

A

1 Oxygen molecule

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6
Q

Globin portion components

A

Two pairs globin chain (2 alpha and 2 non alpha)

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7
Q

Hemoglobin functions

A

Transport of gases

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8
Q

The primary hemoglobin for gas transport

A

Oxyhemoglobin

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9
Q

What are the hemoglobin variants

A
  1. Methemoglobin
  2. Sulfhemoglobin
  3. Carboxyhemoglobin
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10
Q

Hemoglobin variant that leads to cyanosis

A

Sulfhemoglobin

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11
Q

Hgb variant containing Ferrous iron

A

Methemoglobin

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12
Q

Hgb variant that leads to irin binding carbon monoxide

A

Carboxyhemoglobin

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13
Q

Sulfhemoglobin is irreversible process. TRUE OR FALSE

A

True

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