Hematopoiesis And Cells

Question 1

Regulated process of blood cell production

Answer 1

Hematopoiesis

Question 2

The hematopoietically active marrow

Answer 2

Red marrow

Question 3

Where most hematopoiesis occurs

Answer 3

Bone marrow

Question 4

Red marrow can be found in what bones of adults

Answer 4

1. Proximal ends of long bones
2. Skull
3. Sternum
4. Scapulae
5. Ribs
6. Pelvis

Question 5

Hematopoietically inactive marro that consists if fat cells

Answer 5

Yellow marrow

Question 6

What progenitor leads to the production of neutrophil, monocyte, erythrocytic and macrocytic cell lines?

Answer 6

Common myeloid progenitor

Question 7

Progenitor that produces lymphoid cells

Answer 7

Common lymphoid progenitor

Question 8

Stages of RBCs from immature to mature

Answer 8

Pronormoblast
Basophilic normoblast
Polychromatophilic normoblast
Orthochromic normoblast
Reticulocyte
Mature erythrocyte

Question 9

Changes when red cells divide and mature

Answer 9

Size decrease & extruded nucleus

Question 10

Changes in red cell maturation

Answer 10

Size decrease & extruded nucleus

Question 11

Rbc sybthesis is stimulated by

Answer 11

Erythropoietin

Question 12

What organ produces eryhthropoietin

Answer 12

Kidney

*In response to hypoxia

Question 13

Lifespan of RBCs

Answer 13

120 days or almost 4 months

Question 14

How are rbcs removed at the end of their life

Answer 14

Intravascular or extravascular hemolysis

*Contents of cells are recycled or excreted

Question 15

Mature rbcs rely on_____ for energy

Answer 15

Anaerobic glycosis thru Embden-Meyerhof pathway

Question 16

Pathways involved with RBCs

Answer 16

1. Hexose monophosphate shunt
2. Methemoglobin reductase pathway
3. Rapoport Luebering pathway

Question 17

Product of Rapoport-Luebering pathway

Answer 17

2,3-biphosphoglycerate or 2,3-BPG

Question 18

Hexose monophosphate shunt pathway product

Answer 18

Reduced glutathione