Hemoglobin

Question 1

What are the five types of hemoglobin?

Answer 1

A, A2, F, S, and C. S and C are due to mutation

Question 2

What is the molecular structure of hemoglobin A?

Answer 2

2 alpha chains and 2 beta chains

Question 3

What is the adult reference range for hemoglobin A?

Answer 3

greater than 95%

Question 4

What is the newborn reference range for hemoglobin A?

Answer 4

20%

Question 5

What is the molecular structure for hemoglobin A2?

Answer 5

2 alpha and 2 delta chains

Question 6

What is the normal adult reference range of hemoglobin A2?

Answer 6

1.5 to 3.7 percent

Question 7

What is the normal newborn reference range of hemoglobin A2?

Answer 7

less than 1%

Question 8

What is the molecular structure of hemoglobin F?

Answer 8

2 alpha and 2 gamma chains

Question 9

What is the normal reference range of homoglobin F in adults?

Answer 9

less than 2%

Question 10

What is the normal reference range of hemoglobin F in newborns?

Answer 10

50 to 85%

Question 11

What is the molecular structure of hemoglobin S?

Answer 11

valine substituted for glutamic acid in the 6th position of the beta chain

Question 12

What is the molecular structure of hemoglobin C?

Answer 12

Lysine substituted for glutamic acid in the 6th position of the beta chain