Hemodynamics and the Circulatory System Flashcards
What are the three functions of blood?
Transportation, regulation, protection
What does blood regulate?
- PH
- Water in plasma has heat absorbing and coolant properties which help maintain and adjust body temperature
What does blood protect against?
- Clotting of blood protects against excessive blood loss
- WBCs protect against disease through phagocytosis and production of antibodies
What does blood transport?
- Transports O2 from lungs to cell
- Carries CO2 from body cells to lungs
- Transports nutrients from GI tract to body cells
- Carries heat and waste products away from cells
- Transports hormones from endocrine glands to other body cells
What are five characteristics of blood?
- Blood is more dense and more viscous than water and flows more slowly
- Temperature of blood is 38oC (100.4oF)
- Blood has slightly alkaline PH
- Blood makes up about 8% of body weight
- Blood volume is 4-5 liters (1.2 gal) in an average adult female and 5-6 (1.5 gal) in an average adult male
Whole blood is composed of what two components?
- Blood plasma
- Formed elements
- ____ is a watery liquid that contains dissolved substances
- ____ is usually about 55% plasma
Blood plasma
- ____ are cells and cell fragments
- ____ are usually about 45% blood
- ____ are usually more than 99% RBCs of total blood volume
- ____ are usually less than 1% WBCs of total blood volume
Formed Elements
When formed elements are removed from blood, the remaining straw-colored liquid is called ____
Blood plasma
____ is about 91.5% water and 8.5% solutes
Plasma
What are the three types and percentages of plasma proteins that make up the 7% of solutes that are synthesized by the liver?
What is included in the remaining 1.5% of solutes in plasma?
- Electrolytes
- Nutrients
- Regulatory substances such as enzymes and hormones
- Gases and waste products such as urea, Uris acid, creatinine, ammonia and bilirubin
The three components of formed elements of blood include?
____ contain oxygen carrying protein called hemoglobin and do not contain a nucleus
RBCs (erythrocytes)
The percentage of total blood volume occupied by RBCs is called the ____?
Hematocrit
____ are nucleated and do not contain hemoglobin
WBCs (leukocytes)
____ leukocytes include eosinophils, basophils and neutrophils
Granular
____ leukocytes include lymphocytes and monocytes
Agranular
____ function to protect the body against foreign substances, accumulation of damaged cells, and infectious organisms
WBCs
____ are actually cell fragments with pieces of cell membrane that originate from large cells called megakaryocytes that splinter into 2000-3000 fragments
Platelets (thrombocytes)
____ are disc shaped and are not nucleated; help stop blood loss from damaged vessels by forming a platelet plug; release chemicals that promote blood clotting
Platelets
____ form a closed system that carries blood away from the heart to the body tissues and then returns blood from the tissues to the heart
Blood vessels
- Large elastic arteries leave the heart and divide into medium sized muscular arteries that branch to various regions of the body
- Medium sized arteries branch into smaller vessels called ____
Arterioles
When Arterioles enter tissues, they branch into microscopic vessels called ____
Capillaries
- Substances are exchanged between blood and body tissue through the thin capillary walls
- Before leaving tissues, capillaries unite to form very small veins called ____
Venules
- Venules merge to form veins
- Veins carry blood from tissues back to the heart
- Large vessels are nourished from their own blood vessel supply called the ____
Vasa Vasorum
What are the three tunics or coats that Arterial walls have?
- Tunica interna (intima)
- Middle tunica (tunica media)
- Outer coat (tunica externa)
Intima is composed of a thin lining of simple squamous epithelium called ____, a basement membrane and a layer of elastic tissue called the internal elastic lamina
Endothelium
____ is a continuous layer of cells that lines the entire cardiovascular system
Endothelium
____ is the thickest tunic layer
Tunic media
____ Consists of elastic and smooth muscle fibers arranged in rings around the lumen
Tunica media
____ consists of mostly elastic and collagen fibers
Outer coat (tunica externa)
An increase in sympathetic stimulation causes muscle contraction that
reduces the size of the vessel lumen (vasoconstriction)
An decrease in sympathetic stimulation causes muscle relaxation that
widens the size of the vessel lumen (vasodilation)
If an artery is damaged muscles will ____ producing a ____ that limits blood flow and ____ blood loss
contract; vascular spasm; reduces
Largest diameter arteries are called
elastic arteries