Hemodynamics Flashcards
Hemodynamic monitoring
The measurement of pressure, flow, and oxygenation within the cardiovascular system
CVP
term only
Central venous pressure
CVP = RAP
PAWP
Term only
Pulmonary artery wedge pressure
Cardiac output (CO)
The volume of blood in liters pumped by the heart in 1 minute.
Cardiac index
The measurement of the CO adjusted for body surface area (BSA)
Stroke volume (SV)
The volume ejected with each heartbeat
Stroke volume index
The measurement of SV adjusted for BSA
SV
Term only
Stroke volume
SVR
Systemic vascular resistance
- resistance of the systemic vascular bed
- opposition encountered by the left ventricle
PVR
Pulmonary vascular resistance
- resistance of the pulmonary vascular bed
- opposition encountered by the right ventricle
Preload
The volume within the ventricle at the end of diastole
Left ventricular end diastolic pressure (LVEDP)
Left ventricular preload
- Not measured directly; measured in pulmonary artery (PAWP)
PAWP
Pulmonary artery wedge pressure
- measurement of pulmonary capillary pressure
- reflects left ventricular end-diastolic pressure under normal conditions
- Norm: 6-12 mmHg
Contractility
Describes the strength of contractions of the heart
- said to increase when preload is unchanged yet the heart contracts more forcefully
Drugs that increase/improve contractility (+ inotropes)
Epinephrine; norepinephrine [Levophed] Isoproterenol (Isuprel) Dopamine (Intropin) Dobutamine (Dobutrex) Digitalis-like drugs Calcium Milrinone
Drugs that reduce contractility (negative inotropes)
Alcohol Calcium channel blockers Beta-adrenergic blockers Anesthetics, sedatives, barbiturates Some chemo agents
Impedance cardiography (ICG)
A continuous or intermittent, noninvasive method of obtaining CO and assessing thoracic fluid status.
Ejection fraction
Amount of blood pumped out of heart compared to how much is remaining
Normal CO value range
4-8 L/min
HR norm range
60-100 beats/min
Stroke volume (SV) normal range
60-150 mL/beat
PAWP normal range
6-12 mm Hg
CVP/RAP normal range
2-8 mmHg
SVR = ?
[(MAP - RAP) / CO] x 80
Norm CVR: 800-1200 dynes/sec/cm-5
SVR norm range
800-1200 dynes/sec/cm-5
CO = ?
SV x HR
Norm CO: 4-8 L/min
ml/min) = (beats/min) x (ml/beat
What does PAWP correlate/equal to?
PAWP = lung pressure = pulmonary vein pressure = LAP = LVEDP
Normal MAP range
70-105 mm Hg
Normal CI range
2.5-4 liters/min/meter(2)
Drug(s) to reach for when HR is too low?
Atropine
Drug(s) to reach for if the HR is too high?
Beta blockers
Ca Channel blockers
Digoxin
How does the sympathetic nervous system act on the heart?
Will increase HR with intervention
What are the 3 levels of dopamine dosing?
Low – dopaminergic effect – (1-5 mcg/kg/min)
Moderate – beta effect – (5-10 mcg/kg/min)
High – alpha effect – (10-20 mcg/kg/min)
How will the parasympathetic nervous system act on the heart?
Will decrease HR with intervention
What are the 3 determinants of stroke volume?
Preload
Afterload
Myocardial contractility
What may cause a decreased preload?
Hypovolemia
Loss of atrial kick (a-fib)
Venous vasodilation (sepsis, anaphylactic shock)
What are some causes of increased preload?
Ventricular failure
Hypervolemia
renal disease (hyervolemia)
How is the preload measured
Not measured directly (in L ventricle)
- catheter in pulmonary artery (PAWP)
- Left ventricular end diastolic pressure (LVEDP)
PAWP of 18-20 mmHg; Clinical state?
Onset of pulmonary congestion
PAWP of 20-25 mmHg; clinical state?
Moderate pulmonary congestion
PAWP of 25-30 mmHg; clinical state?
Severe congestion
PAWP of > 30 mmHg; clinical state?
Pulmonary edema
What is the objective in treating low preload?
Increase circulating volume
What is the treatment of low preload?
Give fluids (crystalloids or colloids) blood products
What is the objective in treating high preload?
Decrease circulating volume OR venous return
How is high preload treated?
Diuretics (lasix)
Vasodilators
What are some causes of decreased afterload?
Vasodilation
sepsis, vasodilation tx, anaphylactic shock, hypotension
What are some causes of increased afterload?
HTN
Aortic stenosis
Vasoconstriction
Normal CVP/RAP range?
2-8 mm Hg
What is the objective in treating low afterload?
Vasoconstriction
How is low afterload treated?
Vasopressors
(epinephrine, norepinephrine, dopamine (>10), neosynephrine
In treating a patient with low afterload, what is done before drug therapy?
Fluid bolus
What is the objective in treating high afterload?
Decrease resistance to ejection of blood
How is high afterload treated?
Arterial vadodilators (nipride, Primacor (milrinone), nitroglycerin, Cardene) Surgery -- Aortic valve replacement
What are some causes of decreased contractility
Parasympathetic stimulation
Negative inotropics
Metabolic states (hyperK+, myocardial ischemia, hypoxia, acidosis)
What is the objective in treating low contractility?
Improve the force of contraction
How is low contractility treated?
Optimize preload
- positive inotropic drugs
- ventricular assist devices
What are some causes of increased contractility
Sympathetic stimulation
Positive inotropic drugs
Metabolic states (hyperthyroidism)
What is the objective in treating high contractility?
Decrease myocardial work & oxygen consumption
How is high contractility treated?
negative inotropic drugs
cardiac index (CI) = ?
CI = CO/BSA
normal CI = 2.5-4 liters/min/meter(2)
What may interfere with reliable PAWP readings?
Mitral valve disease
High intra-alveolar pressure (ventilators)
In a pulmonary artery (PA) catheter with 4 ports, what are the ports?
- cardiac output balloon
- PAWP distal port
- PA pressure readings proximal port
- CVP reading
Normal pulmonary artery pressures?
25/10 (quarter over dime)
What three things must you “tell a transducer”
Put it to pressure (300 mmHg of pressure in transducer )
Zero the transducer
Line/level the transducer with the source
Important nursing care with an A-line
- Never put meds in an A-line
- be able to See the line (provide some degree of modesty)
- check connections – make sure it is tight
- ensure alarms on
- infection prevention
- Hemorrhaging
What are two invasive techniques for measuring cardiac output?
Intermittent Bolus thermodilution CO (TDCO) Continuous CO (CCO)