Hemodynamics Flashcards
Hemodynamic Principles:
Flow of _____ and factors affecting it
Study of _____ circulation
Hemodynamic Principles:
Flow of BLOOD and factors affecting it
Study of BLOOD circulation
Evaluates:
- Intravascular _______ and ______
- Intracardiac _______
- _______ function
These all affect the body’s ability to ensure adequate tissue ________ and _______
Evaluates:
- Intravascular VOLUME and PRESSURES
- Intracardiac PRESSURES
- CARDIAC function
These all affect the body’s ability to ensure adequate tissue PERFUSION and OXYGENATION
Invasive vs Non-Invasive HD Monitoring
Non-invasive: no device inserted into the body - does not breach skin (BP, HR, O2, U/O, JVD)
Invasive: Breach of skin (Art line, pulm-art catheter, CVP)
Determinants of Oxygen Delivery
Cardiac output x Oxygen Content
- Cardiac output: HR x SV (preload, afterload, contractility)
- Oxygen content: oxygen saturation & hemoglobin
Cardiac Output:
Amount of blood pumped out of the ____ in a _____
CO: ____ x ____
HR: # of _____ of the _____ in a _____
SV: Amount of blood ___ out of the ___ per _____. It is the difference between ______ and ______
Cardiac Output:
Amount of blood pumped out of the LV in a MINUTE
CO: HR x SV
HR: # of CONTRACTIONS of the HEART in a MINUTE
SV: Amount of blood PUMPED out of the LV per BEAT. It is the difference between EDV and ESV
How to calculate EF?
Normal EF?
SV / EDV x 100
50-70%
3 factors that affect stroke volume?
Preload, afterload, and contractility
Contractility:
AKA _______
Ability of the cardiac muscle to _____
Strength of the cardiac muscle to ____ blood from the _____
Primary parameter that affects _____
Increased _______ = Increased ______ = Decreased _______
Contractility:
AKA INOTROPY
Ability of the cardiac muscle to CONTRACT
Strength of the cardiac muscle to PUMP blood from the VENTRICLES
Primary parameter that affects ESV
Increased CONTRACTILITY = Increased SV = Decreased ESV
Medications that Affect Contractility:
Positive Inotropes:
Negative Inotropes:
Digoxin, dopamine, atropine
BB, BBC, lidocaine, adenosine
Electrolytes that increase contractility
Electrolytes that decrease contractility
Increase: HyperMg, HyperCa
Decrease: HypoMg, HyperK, HypoNa
How does HR affect contractility?
Increased HR increases contractility, but sustained tachycardia leads to decompensation - decreased contractility
Vagal stimulation will ________ contractility
Decrease
EDV
ESV
SV
EDV - Amount of blood that fills the ventricles prior to contraction (affects preload)
ESV - Amount of blood that remains in the ventricles after contraction (affected by afterload)
Difference between EDV - ESV (amount of blood ejected)
Ie. If EDV is 100cc and SV is 60cc, then the ESV is 40cc
What is preload?
Degree to which cardiac muscle fibres are ______ prior to _________
Anything that affects ______ will affect preload
Increased ____ = increased ______ = increased _____ = increased ______ = increased _______ (up to a point)
The amount of stretch caused by the EDV
Degree to which cardiac muscle fibres are STRETCHED prior to CONTRACTION
Anything that affects VENOUS RETURN will affect preload
Increased EDV = increased STRETCH = increased PRELOAD = increased CX = increased CO (up to a point)
Frank-Starling Mechanism
- Force of cardiac contraction is directly ______ to the length of the muscle fibre
- The greater the _______, the stronger the ______ = increased ________
- However, after a certain threshold, the stretch will _______ contractility
Frank-Starling Mechanism
- Force of cardiac contraction is directly PROPORTIONAL to the length of the muscle fibre
- The greater the STRETCH, the stronger the CX = increased SV
- However, after a certain threshold, the stretch will DECREASE contractility
Afterload:
The __________ or __________ ventricles must overcome to pump blood out
LV: ______
RV: ______
Any condition that increases the resistance (afterload) will require more ____ to open the semilunar valves and pump blood out
_____ in afterload = _______ SV = ______ ESV
_____ in afterload = _______ SV = ______ ESV
Afterload:
The RESISTANCE or PRESSURE ventricles must overcome to pump blood out
LV: SVR
RV: PVR
Any condition that increases the resistance (afterload) will require more FORCE to open the semilunar valves and pump blood out
INCREASE in afterload = DECREASED SV = INCREASED ESV
DECREASE in afterload = INCREASE SV = DECREASED ESV
How do hyper- and hypo-volemia affect afterload?
How do hyper- and hypo-tension affect afterload?
Hypervolemia = increased AL = decreased SV
Hypovolemia = decreased AL = increased SV
Same with BP