Hemodynamic Effects of Long-term administration of anti HTN agents

Question 1

Describe the effects of long-term administration of centrally acting sympatholitic agents on…

1. Heart rate
2. Cardiac output
3. TPR
4. Plasma Volume
5. Plasma Renin Activity

Answer 1

1. Heart rate: decrease/no change
2. Cardiac output: decrease/no change
3. TPR: Decrease
4. Plasma Volume: Increase/no change
5. Plasma Renin Activity: Decrease/no change

Question 2

Describe the effects of long-term administration of Alpha receptor antagonists on…

1. Heart rate
2. Cardiac output
3. TPR
4. Plasma Volume
5. Plasma Renin Activity

Answer 2

1. Heart rate: Increase/no change
2. Cardiac output: Increase/no change
3. TPR: Decrease
4. Plasma Volume: increase/no change
5. Plasma Renin Activity: decrease

Question 3

Describe the effects of long-term administration of arteriolar vasodilators on…

1. Heart rate
2. Cardiac output
3. TPR
4. Plasma Volume
5. Plasma Renin Activity

Answer 3

1. Heart rate: Increase
2. Cardiac output: Increase
3. TPR: Decrease
4. Plasma Volume: Increase
5. Plasma Renin Activity: Increase

Question 4

Describe the effects of long-term administration of Ca++ channel blockers on…

1. Heart rate
2. Cardiac output
3. TPR
4. Plasma Volume
5. Plasma Renin Activity

Answer 4

1. Heart rate: up or down
2. Cardiac output: up or down
3. TPR: Decrease
4. Plasma Volume: Increase/no change
5. Plasma Renin Activity: Increase/no change

Question 5

Describe the effects of long-term administration of ACE inhibitors on…

1. Heart rate
2. Cardiac output
3. TPR
4. Plasma Volume
5. Plasma Renin Activity

Answer 5

1. Heart rate: No change
2. Cardiac output: no change
3. TPR: Decrease
4. Plasma Volume: No change
5. Plasma Renin Activity: Increase

Question 6

Describe the effects of long-term administration of ARBs on…

1. Heart rate
2. Cardiac output
3. TPR
4. Plasma Volume
5. Plasma Renin Activity

Answer 6

1. Heart rate: no change
2. Cardiac output: no change
3. TPR: decrease
4. Plasma Volume: No change
5. Plasma Renin Activity: increased

Question 7

Describe the effects of long-term administration of direct renin inhibitors on…

1. Heart rate
2. Cardiac output
3. TPR
4. Plasma Volume
5. Plasma Renin Activity

Answer 7

1. Heart rate: no change
2. Cardiac output: no change
3. TPR: Decrease
4. Plasma Volume: no change
5. Plasma Renin Activity: decrease, but renin concentration increases