Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

para > hemo > Flashcards

hemo Flashcards

1
Q

T cruzi Disease

A

Chagas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Tcruzi group

A

Stercoraria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T crusi mulitply host manner

A

discountinous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Tcrzui most heavily infrcted cells

A

Myocytes and reticuloendothelial system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

T cruzi vectors

A

Reduviid Tratoma, Panstrongylus, Rhodnius

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T cruzi stages of deevlopment

A

Amastigote, Promasitote, epimastigote, trypomastigote

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tcruzi stage in bloodstream

A

Trypomastigote

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

T crusi stage in tissue cells

A

Amastigot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

T cruzi stage in vevtor midgut

A

aastigote, epimastogote, promastigote

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Tcruzi stage in hindgut

A

metacyclic trypomastigotes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what parasite and stage oosterior pointed, 2/3 undulations, threadlike flagellum, C U S shaped

A

Trypomastigotes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

T cruzi trypomastigote charactersitic of species

A

kinetoplast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Tcruzi location where thye multiplu

A

Macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Tcruzi method of multipliation

A

hbinary fission as amastigotes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Tcruzi transmission

A

bite broken skin mucous mebrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Tcruzi disease stages

A

acute and chronic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

T cruzi acute phase

A

inflammation of myocardium, fever malaise, lymphadenopathy, Chagomas, Romanas sign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Chagomas

A

furuncle lile lesion, central edema lympahdenopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Romanas sign

A

Conjunctivities, bipalpebral edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

T cruzi chronic stage

A

friboic resctions injure myocsrdium, cardiac conduction system p, enteric nervous system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

T cruzi chronic stage most affected organ

A

aheart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

T cruzi chronic stage symptoms

A

cardiomegaly, arrhytmnia, paliptations, GIT form=achalasia due to emegaesphagus, cosntipation due to megacolon 1/3rd affected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

T cruzi disease diagnosis

A

compelte patient hsitory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

T cruzi disease definitive diagnosis

A

visualize parssites in blood smears using giemsa stain, only in 1st 2 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

T cruzi diagnosiis in chronic stage

A

elisa, hemaglutination , pcr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

t cruzi disease cardiac diagnosis

A

ECG atrial fibrillation, low QRS voltage, cardiomayipathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

T cruzi. disease GIT diagnosis

A

barium esophagogram, barium enema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Tcruzi treatment and sideeffects

A

nifurtimox ( weight loss anorexia behavioral changes) and benznidazole (rashes, bone marrow suppression, neuropathy)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

nifurtimox moa

A

oxidative radicals, dna synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

T cruzi disease epidemiology

A

chagas disease, 10 mil worldwide, latin americas, inwho list pf. eglected diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Tbrucei gambiense and rhodesiense disease

A

HAT african sleeping sickness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

T brucei family

A

Salivaria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

T brucei vector

A

Tsetse fly Glossina

34
Q

T brucei gambiense localise, affects, epidemiology

A

western pand central subsahara, humnas, reservoir dogs pigs sheep, 95%

35
Q

T brucei rhodesiense localize, affects, epi

A

east sfrica, cattle and wild animlas, humans aciddntal, more rapid and fatal 5%

36
Q

T brucei stages

A

epimastigot and trypmastigote

37
Q

T brucei location in body

A

Bloom lymph and spleen CSF

38
Q

what parasite and stage selnder, stumpy, flattened and fusiform, large central karyosome, undulatingmembrane, flagellum

A

trypomastigote

39
Q

HAT initial lesion

A

chancre, then eschar, more common in gambiense

40
Q

HAT 2 stages

A

hemolymphatic stage and meningocephalic stage

41
Q

HAT hemolymphatic

A

fever headache, muscle pain malaise, anemia myocsrditis

42
Q

lymph nodes enlarged nontender rubbery

A

Winterbottoms sign HAT gambeiense

43
Q

HAT hemilymphatic reason

A

damage in tissue due to toxins or immune reactions

44
Q

HAT meningoecephalitic

A

CNS symotms, headache, sleep,apathy, behavour, convuslions speech defects, paralysis

45
Q

deep delayed hyperesethsia

A

kerandals sign HAT meningocephalitic

46
Q

Continously changing surface proteins

A

antigenic variation T brucei

47
Q

T brucei diagnosis

A

trypanosomes in chancre, lymph, CSF, blood

48
Q

T brucei pathognomic for meningoencepahlitic stage

A

increased IgM levels

49
Q

T brucei diagnsotic test

A

Card agglutination test

50
Q

T brucei treatment and efects

A

Suramin sodium for both (fever, rash, renal insufficiency, muscle pain), pentamidine for gambiense (tachycardia hypoglecemia hypotension), melarsoprol for CNS (fatal arsenic ecncephalopathy)

51
Q

Melasroprol second line drug

A

Nitrofurazone and eflornithine

52
Q

Melarsoprol reaction

A

Jarsih Herxheimer reaction febrile epsiode

53
Q

T brucei epidemiology

A

300,00.in subsaharan africacatt

e and game animals like antelopes are reservoir animlas

54
Q

Leishmania 2 types

A

New world (amazonensis, barziliensi, mexiacana, guynensis, chaagsi) old world (tropica, aethipica, major)

55
Q

Leishmania vector

A

Phlebotomus Lutzomyia sandfly

56
Q

Leishmania primary reservoirz

A

Dogs and rodents

57
Q

zleihsmania in mammalian host

A

amastigote

58
Q

Leishmania in vector

A

promastigote

59
Q

what stage and parasite ovoid bodies, live in monocytes, leukocytes, large nucelus,axoneme srise from kinetoplast

A

Amastigote Lesihamnia

60
Q

what stage and parasite ssingle free flagellum from kinetoplast, invade reticuloendothelial cells

A

promastigotes zleishmania

61
Q

leishmania diseases

A

CL, DCL, MCL VL

62
Q

Lieshmania immune system response

A

Leishamnia specific Th1 type CD4+ Tcells, macrophages, cytokines

63
Q

zlishamnia most common form

64
Q

erythematous papul or nodule / orientsl button

A

CL lesihkaniasisis

65
Q

Chiclero ulcer in ears

A

L. mexicana

66
Q

Leptomatous keishmania, localized, non ulcersting papule

67
Q

In 2-5% L braziliense, mucous mmebranes

68
Q

Nasal stiffiness, discharge, esoitaxis, destruction od nasal septum

A

Espundia, MCL

69
Q

Kala azar, by L donovani complex,

70
Q

VL cause

A

spread in spleen liver bone marrow

71
Q

Twice daily fever spikes, chills

72
Q

hepatosplenomegaly efever weakness loss of appetite

A

Subacute chronic VL

73
Q

MCL Th1 response

74
Q

VL th1 response

A

low absent

75
Q

Hypopigmented macules, amlar erythema, nodules, ulcerations

A

post kala azar dermal leishmaniasis

76
Q

leishamnia diagnosis

A

amastigotes in lesions, tissue biopsy

77
Q

Lieshmania skij test positive in , negative in

A

CL MCL, DCL VL

78
Q

Leishamnia treatment

A

sodium stibogouconate, meglumine (abdmonial pain, nausea, arthralgia, arrythmia), drug of choice is amphotericin B, Miltefosine in VL patients

79
Q

Lieshamnia disease of poverty

A

squalid, poor housing malnutrition, weak immune system, lack of resources

80
Q

coinfection leishmania

81
Q

Leishamnia prevention

A

repelents DEET and permethrin, no chemoprohpylaxis

para (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions