Hemeonc11 Flashcards
What can you do for a breast cancer that is mainly influenced by estrogen and progesterone growth factors?
Target the cancer with hormone therapy. (Essentially blocking these growth hormones)
Following a breast bx that is positive for cancer, what is the next step?
Sentinal node bx, and CXR
Why would a CXR be important after a dx of breast cancer?
1) Possible direct infiltration of cancer into chest
2) If there are mets, they’d likely go into systemic circulation and then the lungs
If you are concerned about mets to the liver, what testing would you order?
CT, LFT’s, tumor markers
Common sites for mets from the lungs are
1–brain, then bone and adrenal glands
Neutropenia and bone marrow suppression are oncology emergencies. Why? How are they treated?
Because of high risk for infection, sepsis, fever.
Treated with gram negative abx, and growth factors to promote neutrophil recovery
Hydration Lasix Bisphosphonates Dialysis Are treatments for what oncology emergency?
Hypercalcemia
the initial chemotherapy intended to produce a remission is called?
Induction chemotherapy
The most common mechanism cancer cells use to acquire resistance to chemo involves effluxing the medication. The protein responsible for this is?
p glycoprotein
Chemotherapy after surgery is called?
Adjuvant chemotherapy
Chemotherapy before surgery is called?
Neoadjuvant chemotherapy
A transplant in which the patient receives his own stem cells is called an __________ transplant
autologous
A transplant in which the patient receives stem cells from a donor is called an _____________ transplant
allogenic
immunologic differences between donor and recipient allow transplanted stem cells to attack tumor cells in the host. This is called a _____________________
graft vs tumor effect (yay)
In the flip side, the potentially serious risk of a donor’s cells attacking the recipient is called?
graft vs host disease
