Heme/Onc - short n sweet Flashcards

1
Q

testicular cancer metastasizes where?

A

lung

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2
Q

lung cancer metastasizes where?

A

brain

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3
Q

prostate/breast cancer metastasize where?

A

bone

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4
Q

colon cancer metastasizes where?

A

liver

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5
Q

cervical cancer metastasizes where?

A

peritoneum

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6
Q

side effects of monoclonal antibodies

A

heart failure, stroke, bowel perforation

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7
Q

side effects of enzyme inhibitors

A

neutropenia, thrombocytopenia

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8
Q

side effects of antimicrotubulars

A

vincristine: phlebitis, cellulitis
paclitaxel: neutropenia, peripheral neuropathy, bradycardia

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9
Q

side effects of GnRH analogs

A

impotence, hot flashes

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10
Q

side effects of aromatase inhibitors

A

osteoporosis

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11
Q

side effects of SERMs

A

NVD, stomatitis, alopecia, ulcers

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12
Q

side effects of alkylating agents

A

secondary malignancies

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13
Q

tumor marker alpha-fetoprotein used for

A

hepatocellular carcinoma

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14
Q

tumor marker Bence Jones proteins used for

A

multiple myeloma

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15
Q

tumor marker beta-HCG used for

A

germ cell tumors, hydatidiform moles, choriocarcinoma of uterus

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16
Q

tumor marker BRCA1/2 used for

A

risk of breast/ovarian/prostate cancer

17
Q

tumor marker CA 19-9 used for

A

pancreatic, hepatobiliary cancer

18
Q

tumor marker CA-125 used for

A

ovarian cancer

19
Q

tumor marker CEA used for

A

MAIN ONE: colorectal, but also breast, pancreatic, gastric, hepatobiliary, small cell lung cancer

20
Q

tumor marker PSA used for

A

prostate cancer

21
Q

renal cell cancer & melanoma metastasize where?

A

brain

22
Q

unique side effect of antimetabolites

A

ulcerative stomatitis

23
Q

most common inherited hypercoagulable state

A

activated protein c resistance

24
Q

most common heritable cause of venous thrombosis

A

factor V leiden

25
Q

most common acquired hypercoagulable state

A

malignancy

26
Q

1 in 5 patients with recurrent pregnancy loss have

A

lupus anticoagulant antibodies

27
Q

1 in 5 patients <45 with a stroke have

A

lupus anticoagulant antibodies

28
Q

Lambert-Eaton myasthenia

A

small cell lung cancer

29
Q

lymphatic spread/metastasis

A

carcinomas

30
Q

hematogenous spread/metastasis

A

sarcomas

31
Q

seeding of body cavities

A

ovarian cancer

32
Q

phlebotomy treats

A

hemochromatosis, polycythemia vera

33
Q

90% of those who get carcinoid syndrome have

A

hepatic metastases