Heme/Onc - mostly myeloproliferative stuff

Question 1

Name 5 myeloproliferative disorders.

Answer 1

1. acute leukemias ALL, AML
2. chronic leukemias CLL, CML
3. polycythemia vera
4. essential thrombocytosis
5. myelofibrosis

Question 2

Which leukemia is a kid leukemia?

Answer 2

ALL

Question 3

Which leukemia is an older adult leukemia?

Answer 3

CLL

Question 4

What is the treatment for CML?

Answer 4

imatinib/Gleevec

Question 5

What leukemia is it if you see Auer rods?

Answer 5

AML

Question 6

Who gets polycythemia vera?

Answer 6

60 yr old men

Question 7

What is the big risk from polycythemia vera?

Answer 7

thrombosis

Question 8

What is the treatment for polycythemia vera?

Answer 8

phlebotomy; NO iron supplementation

Question 9

What is the treatment for CLL?

Answer 9

watch and wait; later, chemotherapy

Question 10

What is the giveaway lab result for polycythemia vera?

Answer 10

High hct; above 50% and maybe up to 60%

Question 11

What is the giveaway lab result for essential thrombocytosis?

Answer 11

extremely elevated platelet count; may be over 2,000,000

Question 12

What is the giveaway lab result for primary myelofibrosis?

Answer 12

abnormal RBC morphology - teardrop poikilocytosis

Question 13

What physical exam finding is a giveaway for primary myelofibrosis?

Answer 13

striking splenomegaly

Question 14

What is the treatment for primary myelofibrosis?

Answer 14

support with transfusion and erythropoietin; median 5 year survival

Question 15

What is the treatment for essential thrombocytosis?

Answer 15

oral hydroxyurea

Question 16

Who gets essential thrombocytosis?

Answer 16

women 50-60 yrs old