Heme Onc 1 Flashcards
“Never Let Monkeys Eat Bananas”
WBC differential from highest to lowest.
Neutrophils: 54-62% Lymphocytes: 25-33% Monocytes: 3-7% Eosinophils: 1-3% Basophils: 0-0.75%
What are the causes of eosinophilia?
NAACP
Neoplasia Asthma Allergic process Connective tissue disorder Parasites (invasive)
What binds to the following receptors?
Gp1b
Gp2b-3a
ADP receptor
Gp1b: vWF
Gp2b-3a: Fibrinogen
ADP receptor: ADP
What does the mnemonic “HALT” stand for?
Causes of target cells.
HepC
Asplenia
Liver disease
Thalassemia
A pt has iron deficiency anemia, esophageal webs and atrophic glossitis. What is the name of this conditin?
Plummer-Vinson syndrome
What is succimer used for?
To chelate out lead in a poisoned patient.
“It SUCs to have lead poisoning.”
What will be the lab values for anemia of chronic disease?
Fe: down
TIBC: down (aka- transferring)
Ferritin: up
*body hides Fe in case bacteria are causing the inflammation.
What does the mnemonic FAT RN stand for?
Thrombotic Thrombocytopenic Purpura
Fever, Anemia, Thrombocytopenia, Renal failure, Neurological symps.
**HUS has Anemia, Thrombocytopenia, and Renal failure
What tests for factors I, II, V, VII, and X?
What tests for all factors except VII and XIII?
PT
PTT
What factors is Vit. K essential for?
II, VII, IX, X, and protein C and S
What is Bernard-Soulier syndrome?
Deficiency in GpIb.
think: There is one “b” in Bernard-Soulier
What is Glanzmann thrombasthenia?
Deficiency in GpIIb/IIIa.
think: they both start with G
What do CD15 and CD30 represent?
Reed Sternberg cells in Hodgkins Lymphoma.