Heme Images Flashcards
What are these?

normal RBC

eosinophil

Basophil

Neutrophil

Monocyte

Lymphocyte

Platelets
(small, aneucleate)

Band

Metamyelocyte
What is occuring in the cytoplasm of this neutrophil?

toxic granulation

reactive lymphocyte
(larger nuclei and lots of cytoplasm)
What abnormality is demonstrated by these RBC?

hypochromia
What structural abnormalities are demonstrated in these RBC?

Anisocytosis,
poikilocytosis
What abnormality is demonstrated by this cell?

Polychromasia
(residual mRNA is present in RBC)

Sickle cell

bite cells

schistocyte

Heinz bodies

bite cells

Howell Jolly bodies

Hgb C crystals
What’s the condition?

SCD Hgb SC

sickle cell anemia
What condition?

microcytic hemolytic anemia
(schistocytes)
What condition?

Iron deficiency anemia
(microcytic, hypochromic)
What condition?

Sickle Cell SC
(note central cell and target cells)
What condition?

Megaloblastic/Macrocytic anemia
(large RBC due to DNA synthesis errors; hypersegmented neutrophil)

Howell Jolly Body
What’s the upper left cell?

nucleatued RBC
What condition?

Spherocytosis

basophilic stippling
(Bone marrow)

ringed sideroblasts (in sideroblastic anemia)

spherocyte
What deficiency?

pyruvate kinase

bite cell

AML
(some myelocyte maturation with auer bodies)

acute premyelocytic leukemia
(more mature, pink blasts, stacks of auer rods)

Acute monocytic leukemia

Chronic Myelogenous Leukemia

Acute myeloid leukemia

Myelofibrosis
(tear drop cells)
What condition? (this is bone marrow)

myelofibrosis
What condition?

chronic myelogenous leukemia
What condition?

essential thrmbocythemia (increased number/size of platelets)
What condition?

infectious mono
What condition?

Hodgkin lymphoma
(note RS cell)
What condition?

Essential thrombocythemia
What’s the condition?
(note: hypersegmented neutrophil and abn RBC’s)
pernicious anemia
“This hypersegmented neutrophil is present along with macro-ovalocytes in a case of pernicious anemia. Compare the size of the RBC’s to the lymphocyte at the lower left center.” –WebPath
What are these two abnormal cells?
RBC with Howell-Jolly Bodies
Nucleated RBC
What protein is absent in these RBCs?
spectrin (hereditary sphereocytosis)
What condition (and subtype) is this consistent with?
CML
Philadelphia chromosome (+)
What condition? (this is sectioned vertebral bone)
multiple myeloma
Reed-Sternberg cells (Hodgkin’s)
What’s the condition?
(sorry if this is fuzzy)
AML
What’s the condition?
myelofibrosis
(also thalassemia)
What’s the condition?
(note: hypersegmented neutrophil and abn RBC’s)

pernicious anemia
“This hypersegmented neutrophil is present along with macro-ovalocytes in a case of pernicious anemia. Compare the size of the RBC’s to the lymphocyte at the lower left center.” –WebPath
What are these two abnormal cells?

RBC with Howell-Jolly Bodies
Nucleated RBC
What protein is absent in these RBCs?

spectrin (hereditary sphereocytosis)
What condition (and subtype) is this consistent with?

CML
Philadelphia chromosome (+)
What condition? (this is sectioned vertebral bone)

multiple myeloma

Reed-Sternberg cells (Hodgkin’s)
What’s the condition?
(sorry if this is fuzzy)

AML
What’s the condition?

myelofibrosis
(also thalassemia)