Heme Function & Immunity Disorders Flashcards
Anemia results in deficient RBC count because of a lack of ______ elements or _____ ______ failure
Nutritional elements, bone marrow
What are the 4 types of anemia?
Anemia of CHRONIC disease, pernicious/FOLATE deficiency anemia, IRON-deficiency, APLASTIC anemia
This type of anemia results from impaired bone marrow/bone marrow depression
Aplastic anemia
Which two types of anemia result from low RBC production?
Iron-deficiency anemia, pernicious/folate deficiency anemia
Pernicious/folate deficiency anemia is also called what?
Megaloblastic anemias
This is AKA an INCREASED RBC count and hematocrit greater than 50%
Polycythemia
What are the two types of polycythemia?
Primary, secondary
______ polycythemia is a neoplastic disease of the pluripotent cells of _____ ______
Primary, bone marrow
______ polycythemia is the body’s normal response to hypoxia/hypoxemia
Secondary
Mononucleosis is an infection of ______ ____ virus. You will have enlarged _____ _____
Epstein Barr virus, lymph nodes
What are the four types of leukemia?
Acute lymphocytic, Acute myelogenous
Chronic lymphocytic, Chronic myelogenous
This type of leukemia occurs mostly in children
Acute lymphocytic leukemia (ALL)
This type of leukemia occurs mostly in older adults
Acute myelogenic leukemia (AML)
Leukemia is a cancer of ________ ______ cells
Hematopoietic progenitor cells
This is the MOST common type of leukemia, primarily with ___ cells
Chronic lymphocytic leukemia (CLL), B
This type of leukemia will show infections, fever, weight loss; this cancer is _______
Chronic myelogenous leukemia (CML), terminal
This type of lymphoma makes up 83% of cases; infection with HIV, EBV
NON-Hodgkin’s
This type of lymphoma makes up 17% of cases; is an abnormal ____ ______ line
Hodgkin’s, B cell
This is one of the most common types of blood cancers in the US!
Lymphoma
There are MANY lymph nodes involved in this type of lymphoma
NON-Hodgkin’s
There’s only a localized, single group of lymph nodes involved in this type of lymphoma
Hodgkin’s
In multiple myeloma, ______ is released into the bloodstream. (Man goes to chiropractor for back pain, then is diagnosed with multiple myeloma!)
Calcium
This is when abnormal B cells form tumors (produce abnormal antibodies)
Multiple myeloma
What are some symptoms of multiple myeloma?
Immune depression, increased blood viscosity (from proteins), proteins infiltrate organs
_________ disorders are an excessive or inappropriate activation of the _______ system
Hypersensitivity, immune
What are the 4 types of hypersensitivity disorders?
I, II, III, IV
Type I hypersensitivity disorder is an _____-mediated disorder. What’s an example?
IgE-mediated; environmental allergen
Type II hypersensitivity disorder is an _____-mediated disorder. What’s an example?
Antibody-mediated; transfusion reaction
Type III hypersensitivity disorder is a _____-mediated disorder.
Complement;
Type IV hypersensitivity disorder is a _____-mediated disorder.
Cell
This blood type is the universal DONOR, meaning they have ___ antigens on the surface
O- ; no antigens
This blood type is the universal RECIPIENT, meaning they have ___ antigens on the surface
B+ ; all the antigens
Type A blood would have __ antigens and __ antibodies
A, B
Type B blood would have __ antigens and __ antibodies
B, A
Type AB blood would have __ antigens and __ antibodies
AB, no antibodies
What causes transfusion reactions?
ABO incompatibility; previous exposure to RBC content
___ __ and _____ are needed to synthesize protein C to prevent excessive ________
Vit K, calcium, coagulation
How does HIV affect cells?
HIV enters T cell, replicates inside it, then destroys it
