Heme Flashcards
Temp above 38C for one hour or a single temp>38.3 w absolute Neutrophil Count <1,000
neutropenic fever, admit and get blood cultures
A Malignant mass causes compression of the Superior Vena Cava
SVC syndrome
Chest Pain, Dyspnea, Distended neck Veins
Tachycardia, narrow pulse pressure, hypotension, distended neck veins, muffled heart tones, and pulsus paradoxus
Echocardiogram, Chest Xray, EKG:LOW AMPLITUDE
Neoplastic Cardiac Tamponade/Malignant Pericardial Effusion
hemolytic anemia/microangiopathic syndromes
TTP Thrombotic Thrombocytopenic Purpura- CNS abnormalities, renal disease, fever, thrombocytopenia, microangiopathic hemolytic anemia
HUS- Hemolytic Uremia Syndrome- acute nephropathy to renal failure, thrombocytopenia, microangiopathic hemolytic anemia
associated with platelet defects
TTP, HUS, Medications, Antiplatelet Antibodies, DIC
liver disease affects
vit K clotting factors
bleeding n renal disease can cause
low platelets and deficiency of coagulation factors secondary to uremic toxins
how to tx bleeding disorders
Platelets, FFP, vit K, IV Fluid, PRBC, Ionotrops, Cryoprecipitate
pts on ASA/plavix need to give platelets
pts on heparin/coumadin/xarelto give FFP
how to tx hemophilia
Replace missing Factor, If factor is unknown give FFP
a-8
b-9
bone marrow failure or splenic sequestration – dyspnea, weakness, CHF, shock. (blood goes into spleen and doesn’t come out)
aplastic crisis
tx w/IVF and PRBCs
Type and Crossmatch
(order if likelihood is high) for PRBC transfusion
type and screen
(order if likelihood to transfuse is low) each take 15-30 minutes T&S does not check for blood compatibility, each check for ABO/Rh and presence of antibodies
when to transfuse
Hg<7
Given when Fibrinogen is suspected to be low;DIC, Amniotic Fluid Embolus, Mass Transfusion, Liver Disease, etc
cryo
