Hematopoiesis Flashcards

1
Q

At what age does hematopoiesis in all marrow cavities end?

A

age of 4

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2
Q

In adults, hematopoiesis occurs in

A

axial skeleton and long bones (red marrow)

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3
Q

What are the growth factors that are non-lineage specific and act on both pleuripotent and multipotential stem cells?

A

IL-3, 7

GM-CSF (granulocyte-monocyte)

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4
Q

What are the lineage-specific growth factors?

A

G-CSF, M-CSF, IL-5, EPO, TPO

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5
Q

Cells that can give rise to all of the cell types that make up the body

A

Pluripotent Stem Cells

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6
Q

Cells that differentiate into either lymphoid or myeloid (non-lymphoid) cells

A

Multipotential (hematopoietic) Stem Cells

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7
Q

What is the order to hematopoietic stem cell development?

A

Hematopoietic –> Progenitor –> Precursor –> Differentiated Cells

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8
Q

Another term to describe reticulocyte?

A

Polychromatic erythrocyte

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9
Q

What is the last stage of erythropoiesis capable of division (mitosis)?

A

Polychromatophilic erythroblast

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10
Q

What is the last stage of granulopoiesis capable of division (mitosis)?

A

Myelocyte

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11
Q

What cells are predominant in adult bone marrow?

A

fat cells

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12
Q

There are more myeloid cells than _____ in adult bone marrow

A

erythroid cells

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13
Q

What is the life span of RBCs?

A

120 days

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