hematopoiesis

Question 1

what is the first site of hematopoiesis?

Answer 1

yolk sac

Question 2

All newborns have extremely high

Answer 2

erythropoietin, nucleated red cells, and reticulocyte count leading to high HH levels

Question 3

At around 3 months of age to puberty Hg will be at

Answer 3

a low of 10, Hct 30, physiologic anemia

Question 4

where is erythropoieten made?

Answer 4

90% in the kidneys

10% in liver

Question 5

60% polys/40% lymph in adults and newborns

Answer 5

Kids 40% polys 60% lymph bc they are making immunoglobulins

Question 6

normal platelet amount

WBC

Answer 6

(200)

5-10

Question 7

what do you typically use in a transfusion?

Answer 7

just the red cells, unless there is hemorrhage

Question 8

what has to match in a transfusion?

Answer 8

donor RBC antigen and recipient’s plasma antibodies

Question 9

blood type A has these two subtypes

Answer 9

A1 and A2, A2 reacts weaker therefore A2 B may be misdiagnosed as B

Question 10

what are the 3 rh alleles??

Answer 10

Ce, Ee, D or no D

Question 11

this is IgG and crosses the placenta

Answer 11

Rh factor,gets more severe with each child

Question 12

this is IgM and does not cross the placenta

Answer 12

red cell blood type (ABO)

Question 13

MCC hemolytic transfusion rxn

Answer 13

personnel error

Question 14

what are some complications of blood transfusions

Answer 14

hemolytic shock

• urticaria
• pyrexia
• rigors
• lumbar pain
• SOB
• HA, vomiting

Question 15

what should you do if a transfusion rxn happens

Answer 15

send specimen to lab

Question 16

what type of cell is most common for transfusion rxn?

Answer 16

WBC-febrile rxn

Question 17

what diseases can you get from a transfusion

Answer 17

Hep B
Hep C
CMV
EBV
Malaria
HIV