Hematology Transfusion Medicine Flashcards
Transfusion of one unit of PRBCs raises
the hematocrit level by ….?
and the Hb level by ……?
HCT by 3%
Hb by 1 g/dl ( 10 g/L)
Platelet transfusions in neurosurgery or active bleeding
Plt < 100
Platelet transfusions in undergoing general surgery
Plt < 50
Platelet transfusions in acute promyelocytic leukemia
Plt < 30 - 50
Platelet transfusions to prevent spontaneous bleeding in most stable, afebrile patients
Plt < 10
Transfusion complications
Hemolytic reaction
Non hemolytic reaction
Hemolytic reactions
Acute ( fever , flank pain, hypotension, bleeding, DIC, hemoglobinuria,death)
Delayed ( 7-14 days after transfusion, +DAT )
Non hemolytic reactions
- TACO
2.TRALI
3.febrile
4.allergic reaction
TRALI treatment
Supportive
O2
Mechanical ventilation
SOB, fever , Hypotension, no signs of volume overload
TRALI
TACO treatment
Diuretics
Slower rate of blood administration
Respiratory distress, elevated CVP, high BNP , pulmonary Odema
TACO