Hematology FINAL EXAM Flashcards

1
Q

What organ converts heme?

What does it convert heme into?

A

Liver

Bilirubin

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2
Q

Where are RBCs destroyed?

A

Spleen

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3
Q

What fluid is bilirubin excreted in?

A

Bile

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4
Q

What is buffy coat preparation useful for?

A
  • To recognize rare cells

- To make it easier to do differential for leukopenia

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5
Q

What are the important components for blood clotting?

A
  • Calcium
  • Fibrinogen
  • Platelets
  • Prothrombin
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6
Q

What clotting factor is affected by being stored in the refrigerator during INR testing?

A

Factor VII

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7
Q

What is Primary Hemostasis?

A

Platelet Plug Formation

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8
Q

What is Secondary Hemostasis

A

Formation of blood clot

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9
Q

What is the anchoring of platelets to the Von Willebrand Factor known as?

A

Adhesion

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10
Q

What is the adhesive protein secreted by endothelial cells ?

A

vWF

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11
Q

What tests are for intrinsic and common pathways?

A

APPT or PTT

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12
Q

What is INR affected by?

A

Coumadin and Warfarin

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13
Q

True or false: Diluent is a bad conductor of electricity?

A

False, it is a good conductor of electricity

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14
Q

True or false: diluent allows the cells to be read one at a time?

A

True

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15
Q

What is the most abundant immunoglobulin in the body?

A

IgG

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16
Q

Where are antigens located and what is an antigen?

A
  • Located on surface of the cells

- A foreign particle

17
Q

Where are antibodies located and what are they?

A
  • Located in the plasma

- They fight off antigens

18
Q

What is erythroblastosis fetalis?

A

HDN - Hemolytic Disease of the Newborn

19
Q

What is TIBC and what blood tubes are required for it?

A
  • Total Iron Binding Capacity

- SST

20
Q

What are thrombocytes?

A
  • Also known as platelets
21
Q

What produces thrombocytes and platelets?

A

Megakaryocytes

22
Q

Define hemoconcentration

A

increase in non-filterable blood components and decrease in plasma

23
Q

How is the rate at which the blood falls in an ESR test measured?

24
Q

True or false: ESR is increased in sickle cell anemia and polycythemia?

A

FALSE, it’s decreased

25
When is ESR increased?
During pregnancy, inflammation, hemolysis, cancer
26
What speed do you centrifuge ESR blood tubes?
500 - 4,000 rpm
27
Does poikilocytosis increase or decrease rouleaux formation?
decrease
28
What else decreases ESR?
Temperature higher than 25 degrees, hemolysis, anemia
29
What stain is used to stain granules in the cytoplasm?
May-Grunwald stain
30
What is Giemsa stain used for?
to stain inclusion bodies in blood cells
31
What is Leishman's stain used for?
for differential
32
What does a low hematocrit result in?
Anemia
33
What does a high hematocrit result in?
Polycythemia
34
Which leukocytes phagocytize dead cells and foreign particles?
Monocytes
35
What leukocytes are increased in a bacterial infection?
Neutrophils
36
What does a MICROHEMATOCRIT measure?
volume of RBC in whole blood
37
What does differential measure?
proportion of WBC in whole blood