Hematology FINAL EXAM

Question 1

What organ converts heme?

What does it convert heme into?

Answer 1

Liver

Bilirubin

Question 2

Where are RBCs destroyed?

Answer 2

Spleen

Question 3

What fluid is bilirubin excreted in?

Answer 3

Bile

Question 4

What is buffy coat preparation useful for?

Answer 4

• To recognize rare cells

- To make it easier to do differential for leukopenia

Question 5

What are the important components for blood clotting?

Answer 5

• Calcium
• Fibrinogen
• Platelets
• Prothrombin

Question 6

What clotting factor is affected by being stored in the refrigerator during INR testing?

Answer 6

Factor VII

Question 7

What is Primary Hemostasis?

Answer 7

Platelet Plug Formation

Question 8

What is Secondary Hemostasis

Answer 8

Formation of blood clot

Question 9

What is the anchoring of platelets to the Von Willebrand Factor known as?

Answer 9

Adhesion

Question 10

What is the adhesive protein secreted by endothelial cells ?

Answer 10

vWF

Question 11

What tests are for intrinsic and common pathways?

Answer 11

APPT or PTT

Question 12

What is INR affected by?

Answer 12

Coumadin and Warfarin

Question 13

True or false: Diluent is a bad conductor of electricity?

Answer 13

False, it is a good conductor of electricity

Question 14

True or false: diluent allows the cells to be read one at a time?

Answer 14

True

Question 15

What is the most abundant immunoglobulin in the body?

Answer 15

IgG

Question 16

Where are antigens located and what is an antigen?

Answer 16

• Located on surface of the cells

- A foreign particle

Question 17

Where are antibodies located and what are they?

Answer 17

• Located in the plasma

- They fight off antigens

Question 18

What is erythroblastosis fetalis?

Answer 18

HDN - Hemolytic Disease of the Newborn

Question 19

What is TIBC and what blood tubes are required for it?

Answer 19

• Total Iron Binding Capacity

- SST

Question 20

What are thrombocytes?

Answer 20

• Also known as platelets

Question 21

What produces thrombocytes and platelets?

Answer 21

Megakaryocytes

Question 22

Define hemoconcentration

Answer 22

increase in non-filterable blood components and decrease in plasma

Question 23

How is the rate at which the blood falls in an ESR test measured?

Answer 23

mm/hr

Question 24

True or false: ESR is increased in sickle cell anemia and polycythemia?

Answer 24

FALSE, it’s decreased

Question 25

When is ESR increased?

Answer 25

During pregnancy, inflammation, hemolysis, cancer

Question 26

What speed do you centrifuge ESR blood tubes?

Answer 26

500 - 4,000 rpm

Question 27

Does poikilocytosis increase or decrease rouleaux formation?

Answer 27

decrease

Question 28

What else decreases ESR?

Answer 28

Temperature higher than 25 degrees, hemolysis, anemia

Question 29

What stain is used to stain granules in the cytoplasm?

Answer 29

May-Grunwald stain

Question 30

What is Giemsa stain used for?

Answer 30

to stain inclusion bodies in blood cells

Question 31

What is Leishman’s stain used for?

Answer 31

for differential

Question 32

What does a low hematocrit result in?

Answer 32

Anemia

Question 33

What does a high hematocrit result in?

Answer 33

Polycythemia

Question 34

Which leukocytes phagocytize dead cells and foreign particles?

Answer 34

Monocytes

Question 35

What leukocytes are increased in a bacterial infection?

Answer 35

Neutrophils

Question 36

What does a MICROHEMATOCRIT measure?

Answer 36

volume of RBC in whole blood

Question 37

What does differential measure?

Answer 37

proportion of WBC in whole blood