Hematology and Coagulation Flashcards

1
Q

Normal values for MCH

A

between 27 and 34pg

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2
Q

Normal values for MCHC

A

Normal values are 33-38%

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3
Q

Normal values for MCV

A

less than 80mm3 means that the cells are microcytic
greater than 100mm3 means that the cells are macrocytic
80-100mm3 means the cells are normocytic

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4
Q

Glucagon is found in

A

The pancreas

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5
Q

Difference between glucagon and glycogen

A

Glycogen is stored in the liver, glucagon is secreted by the pancreas

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6
Q

What is billirubin?

A

A waste product from the breakdown of hemoglobin that is formed in the liver and excreted in the bile

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7
Q

What is a BUN test used for?

A

Measures nitrogen portion of urea/ It is formed in the liver and is the end product of protein catabolism

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8
Q

What is the GTT test

A

Glucose tolerance test. Pt is fasting, and glucose should not exceed more than 100gm/dL at start of test or 180gm/dL 1 hour later

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9
Q

Cations in the blood

A

sodium (Na+)
potassium (K+)
calcium (Ca++)
magnesium (Mg++)

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10
Q

Anions in the blood

A

chloride (Cl-)
bicarbonate (HCO3-)
phosphate (HPO4-)
sulfate (SO4–)

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11
Q

What does the posterior pituitary gland secrete?

A

IDK

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12
Q

What is hemophilia?

A

defect in coagulation cascade, inherited, sex-linked, recessive

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13
Q

Clotting process

A
  1. Vasoconstriction
  2. blood flow
  3. Platelet aggregation
  4. Platelet plug
  5. Coagulation factors (I and II)
  6. Fibrin mesh (chemostasis)
  7. Fibrinolysis with ATP (platelets and factor VIII)
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14
Q

How many days should you stop aspirin before any procedures are done

A

7-10 days

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15
Q

Normal pH of blood

A

7.35-7.45

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16
Q

Poisonous plants

A
Castor beans
Oleander
Peach leaves
Tobacco
Cocaine
Marijuana
Opiates
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17
Q

Normal levels of platelets

A

150,000-400,000/mm3

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18
Q

Natural Anticoagulants

A

Heparin, Antithrombin, Plasminogen

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19
Q

What are lipid tests used for?

A
Used to assess:
 cardiac risk 
 cholesterol
 triglycerides
 high-density lipoprotein (HDL)
 low-density lipoprotein (LDL)
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20
Q

Another name for folic acid deficiency

A

megaloblastic anemia

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21
Q

What is aplastic anemia?

A

a condition in which the bone marrow does not make enough new blood cells

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22
Q

Etiology of sickle cell

A

Inherited,

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23
Q

What is ESR?

A

Erythrocyte Sedimentation Rate: This is the rate at which RBCs settle out of unclotted blood within 60 minutes

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24
Q

What is Narcan?

A

Treatment for narcotic addiction

25
Q

How do cells look in iron deficiency anemia?

A

Cells are microcytic and hypochromic

26
Q

What is CK?

A

Creatinine. This test is used to measure the renal function and glomerular filtration rate, often in conjunction with the BUN

27
Q

What is creatinine used to identify?

A

Acute or chronic renal failure, lupus, gigantism, acromegaly, shock, bladder cancer, leukemia, hypertension, acute MI, CHF and diabetic nephropathy. It is decreased in pregnancy, muscular dystrophy, eclampsia and debilitation disorders

28
Q

What do we use a calcium analysis for?

A

To assess:
thyroid & parathyroid function
calcium metabolism
malignant disease

29
Q

Erythropenia

A

a decrease in RBC count

30
Q

Erythocytosis

A

an abnormal increase in RBCs (usually seen in patients with dehydration, severe burns, polycythemia vera, and living at high altitudes

31
Q

Normal sized RBC

A

Normocytiv

32
Q

Larger than normal RBCs

A

Macrocytic

33
Q

Smaller than normal RBCs

A

Microcytic

34
Q

Pale cells

A

Hypochromic

35
Q

Basophilic stippling

A

Precipitation of RNA

36
Q

Polychromic

A

various colors

37
Q

Leukocytosis

A

An increase in WBC

38
Q

Leukopenia

A

A decrease in WBC

39
Q

Thrombocytopenia

A

A decrease in the number of platelets

40
Q

Thrombocytosis

A

An increase in the number of platelets

41
Q

What is EDTA?

A

Ethyleneaminetetra-acetic acid, a anticoagulant

42
Q

Arteriosclerosis

A

Hardening of arteries

43
Q

Atherosclerosis

A

Accumulation of fatty deposits on the walls of coronary arteries

44
Q

Used to diagnose gout

A

Uris acid

45
Q

Where do we find an increase in iron?

A

Hemochromatosis

46
Q

What enzymes are released when there is a heart attack?

A
Lactic dehydrogenase (LDH)
Creatine phosphokinase (CPK)
47
Q

What enzymes are released when there is a heart attack?

A
Lactic dehydrogenase (LDH)
Creatine phosphokinase (CPK)
48
Q

Half life of a drug

A

The time it takes to eliminate 50% of a drug

49
Q

Therapeutic range

A

Range within a clinical response is achieved without toxic effects

50
Q

What is in a thyroid panel?

A

T3, T4, TSH, thyroglobulin

51
Q

Hepatitis can be caused by

A
Bacteria
Drugs
Toxins
Alcohol
Viruses
52
Q

Arterial blood gases tests:

A

Ventilation
Oxygenation
Acid base balance

53
Q

What is PCO2?

A

Partial pressure of carbon dioxide. The reflection of alveolar ventilation based on the pressure CO2 exerts in the blood.

54
Q

MCV=

A

(Hematocrit/RBC) x 10

55
Q

MCH=

A

(Hemoglobin/RBC) x 10

56
Q

MCHV=

A

(Hemoglobin/ hematocrit) x 100

57
Q

MCV=

A

(Hematocrit/RBC) x 10

58
Q

MCH=

A

(Hemoglobin/RBC) x 10

59
Q

MCHV=

A

(Hemoglobin/ hematocrit) x 100