Hematology Flashcards
Symptoms of hemophilia
bleeding into joints/muscle…..plt disorders usually bleed out of gums or vagina
Factor replacement in hemophilia
8 (A)?
9 (B)?
Hemophilia A (8) - 1 unit/kg raises 2% Hemophilia B (9) - 1 unit/kg raises 1%
life threatening bleed give 50 units/kg for Hemophilia A
and 100 units/kg for hemophilia B
TTP
mneumonic, tx
FAT RN
fever, anemia, thrombocytopenia, renal, neuro
FFP, heme consult, steroids
HUS
Causes
Pathophys
Tx
undercooked hamburger meat shiga toxin is produced by gi tract by E. Coli prodromal gastroenteritis/fever irritability, lethargy, renal failure supportive care...aggressively
Sickle Cell Crisis (3 types)
HIV (hemolytic, infectious, vassocclusive)
sickle cell infection encapsulated bacterias
HIB, strep pneumonia, salmonella (osteo)
are bilirubin and ldh elevated in sickle cell crisis
yes…usually are from hemolysis
1 infectious cause of acute chest syndrome in sc patient
C. pneumonia
tx for CVA in sickle cell patient
exchange transfusion