Hematology Flashcards

1
Q

Symptoms of hemophilia

A

bleeding into joints/muscle…..plt disorders usually bleed out of gums or vagina

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2
Q

Factor replacement in hemophilia
8 (A)?
9 (B)?

A
Hemophilia A (8) - 1 unit/kg raises 2%
Hemophilia B (9) - 1 unit/kg raises 1%

life threatening bleed give 50 units/kg for Hemophilia A
and 100 units/kg for hemophilia B

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3
Q

TTP

mneumonic, tx

A

FAT RN
fever, anemia, thrombocytopenia, renal, neuro
FFP, heme consult, steroids

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4
Q

HUS
Causes
Pathophys
Tx

A
undercooked hamburger meat
shiga toxin is produced by gi tract by E. Coli
prodromal gastroenteritis/fever
irritability, lethargy, renal failure
supportive care...aggressively
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5
Q

Sickle Cell Crisis (3 types)

A

HIV (hemolytic, infectious, vassocclusive)

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6
Q

sickle cell infection encapsulated bacterias

A

HIB, strep pneumonia, salmonella (osteo)

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7
Q

are bilirubin and ldh elevated in sickle cell crisis

A

yes…usually are from hemolysis

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8
Q

1 infectious cause of acute chest syndrome in sc patient

A

C. pneumonia

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9
Q

tx for CVA in sickle cell patient

A

exchange transfusion

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