Hematology Flashcards
iron labs in iron def?
decreased transferrin saturation, increased calculated serum TIBC levels, and decreased serum ferritin levels.
Why does ferritin level go up in anemia of inflammation?
b/c ferritin is acute phase reactant, so it can mask iron def anemia
How to tx iron deficiency anemia with Hbg level >7/asx?
oral ferrous sulfate
only time to use parenteral/IV iron?
in pts who get dialysis
Which anemia is characterized by spherocytes on the peripheral blood smear and a positive direct antiglobulin (Coombs) test?
autoimmune hemolytic anemia (warm)
Which anemia with Spherocytes, negative direct Coombs test, osmotic fragility test demonstrating increased erythrocyte fragility in hypotonic saline compared with normal erythrocytes?
hereditary spherocytosis
What do you see on blood smear in microangiopathic hemolytic anemia?
shistocytes
How to distinguish between anemia of chronic disease and CKD?
inappropriately low retic count for level of anemia present in kidney disease anemia; low TIBC and increased ferritin in chronic dis anemia
long term tx for sickle cell pts with >3 acute chest syndromes yearly?
hydroxyurea
After sickness of fevers and arthralgias, what can happen to sickle cell pts?
it’s parvovirus b19 which causes aplastic crisis
What disease should be suspected in microangiopathic hemolytic anemia and thrombocytopenia?
thrombotic thrombocytopenic purpura
