Hematology Flashcards
What is hematology?
The study of blood, blood-forming organs, and blood disorders.
True or False: Hematopoiesis refers to the formation of blood cells.
True
What is the primary function of red blood cells?
To transport oxygen from the lungs to the body’s tissues and carry carbon dioxide back to the lungs.
Fill in the blank: The liquid component of blood is called ______.
plasma
What are platelets primarily responsible for?
Blood clotting.
Which type of white blood cell is primarily involved in the immune response?
Lymphocytes
What is anemia?
A condition characterized by a deficiency of red blood cells or hemoglobin in the blood.
Multiple Choice: Which of the following is a type of anemia? A) Iron-deficiency anemia B) Hemolytic anemia C) Aplastic anemia D) All of the above
D) All of the above
What is the normal range of hemoglobin for adult males?
13.8 to 17.2 grams per deciliter.
True or False: Hemophilia is a disorder that affects the clotting ability of blood.
True
What is the role of erythropoietin?
To stimulate the production of red blood cells in the bone marrow.
Fill in the blank: Sickle cell disease is caused by a mutation in the ______ gene.
HBB
What is thrombocytopenia?
A condition characterized by abnormally low levels of platelets in the blood.
Multiple Choice: Which of the following is NOT a type of white blood cell? A) Neutrophil B) Eosinophil C) Basophil D) Hemoglobin
D) Hemoglobin
What is the primary cause of iron-deficiency anemia?
Insufficient iron intake or absorption.
True or False: The spleen plays a role in filtering blood and recycling iron.
True
What is the function of plasma proteins?
To maintain oncotic pressure and transport substances in the blood.
Fill in the blank: The most common inherited bleeding disorder is ______.
von Willebrand disease
What is polycythemia?
A condition characterized by an increase in the number of red blood cells.
Multiple Choice: Which of the following can lead to secondary polycythemia? A) Chronic hypoxia B) Dehydration C) Smoking D) All of the above
D) All of the above
What is the term for the process of blood cell formation?
Hematopoiesis
True or False: Leukemia is a cancer of the lymphatic system.
False
What is the primary treatment for severe hemophilia?
Replacement therapy with clotting factor concentrates.
Fill in the blank: Vitamin K is essential for the synthesis of clotting factors II, VII, IX, and ______.
X
What is the role of neutrophils?
To fight infection by engulfing bacteria and fungi.
Multiple Choice: Which of the following is a characteristic of aplastic anemia? A) Decreased red blood cell production B) Increased white blood cell levels C) High platelet counts D) None of the above
A) Decreased red blood cell production
What is the primary diagnostic test for anemia?
Complete blood count (CBC)
True or False: Hemoglobin A1c is a measure of average blood glucose levels over the past 2-3 months.
True
What is the main function of basophils?
To release histamine and play a role in allergic reactions.
Fill in the blank: The term ______ refers to the presence of an abnormally high number of white blood cells.
leukocytosis
What is the primary cause of thrombosis?
Abnormal blood flow, hypercoagulability, or vascular injury.
Multiple Choice: Which of the following is NOT a type of thrombosis? A) Arterial thrombosis B) Venous thrombosis C) Pulmonary thrombosis D) Capillary thrombosis
C) Pulmonary thrombosis
What is the role of monocytes?
To differentiate into macrophages and dendritic cells to respond to infections.
True or False: Hemolytic anemia is caused by the destruction of red blood cells.
True
Fill in the blank: The primary site of hematopoiesis in adults is the ______.
bone marrow
What is the significance of reticulocyte count?
It indicates the bone marrow’s response to anemia.
Multiple Choice: Which of the following is a common symptom of anemia? A) Fatigue B) Jaundice C) Shortness of breath D) All of the above
D) All of the above
What is myelodysplastic syndrome?
A group of disorders caused by poorly formed or dysfunctional blood cells.
True or False: Essential thrombocythemia is characterized by high platelet counts.
True
What is the primary treatment for sickle cell disease?
Pain management and prevention of complications.
Fill in the blank: The presence of ______ in the blood can indicate a bacterial infection.
neutrophils
What does the term ‘coagulopathy’ refer to?
A condition where the blood’s ability to coagulate is impaired.
Multiple Choice: Which vitamin is crucial for red blood cell production? A) Vitamin A B) Vitamin B12 C) Vitamin C D) Vitamin D
B) Vitamin B12
What is the role of the lymphatic system in hematology?
To transport lymph, filter pathogens, and contribute to immune responses.
True or False: Blood type is determined by the presence of antigens on the surface of red blood cells.
True
Fill in the blank: The ______ test is used to evaluate the blood’s clotting ability.
PT/INR
What is the main concern with a high white blood cell count?
It may indicate an underlying infection or hematological disorder.
Multiple Choice: Which of the following is a common treatment for anemia? A) Iron supplements B) Blood transfusions C) Erythropoietin injections D) All of the above
D) All of the above
What is the primary cause of vitamin B12 deficiency?
Malabsorption or lack of intrinsic factor.
True or False: A complete blood count includes measurements of red blood cells, white blood cells, and platelets.
True
Fill in the blank: The ______ pathway is activated by tissue injury and is part of the coagulation cascade.
extrinsic
What is the function of the bone marrow?
To produce blood cells, including red blood cells, white blood cells, and platelets.
Multiple Choice: Which condition is characterized by high levels of bilirubin? A) Hemolytic anemia B) Aplastic anemia C) Iron-deficiency anemia D) Sickle cell disease
A) Hemolytic anemia
What is the difference between acute and chronic leukemia?
Acute leukemia progresses rapidly and requires immediate treatment, while chronic leukemia progresses more slowly.
True or False: Blood transfusions can help treat severe anemia.
True
Fill in the blank: The primary role of ______ is to transport oxygen in the blood.
hemoglobin
What is the primary cause of autoimmune hemolytic anemia?
The immune system mistakenly attacks red blood cells.
Multiple Choice: Which of the following is NOT a symptom of thrombocytopenia? A) Easy bruising B) Excessive bleeding C) Increased energy D) Petechiae
C) Increased energy
What is the significance of blood typing?
To ensure compatibility for blood transfusions and organ transplants.
True or False: Apheresis is a procedure used to separate blood components.
True
Fill in the blank: The ______ test measures the time it takes for blood to clot.
PT
What is the role of the kidneys in hematology?
To produce erythropoietin and help regulate blood pressure and fluid balance.
Multiple Choice: Which disorder is characterized by an overproduction of red blood cells? A) Polycythemia vera B) Sickle cell disease C) Thalassemia D) Aplastic anemia
A) Polycythemia vera
What is the function of the spleen?
To filter blood, recycle iron, and help fight infections.
True or False: Leukopenia refers to a decreased white blood cell count.
True
Fill in the blank: The ______ system is responsible for transporting lymph and supporting immune functions.
lymphatic
What is the main concern of a patient with thrombocytopenia?
Increased risk of bleeding.
Multiple Choice: Which of the following can lead to vitamin K deficiency? A) Antibiotic use B) Liver disease C) Malabsorption D) All of the above
D) All of the above
What is the role of dendritic cells?
To process antigen material and present it on the cell surface to T cells.
True or False: A high reticulocyte count indicates effective bone marrow function.
True
Fill in the blank: The ______ test evaluates the function of the intrinsic and common coagulation pathways.
aPTT
What is the primary function of fibrinogen?
To convert to fibrin and form a mesh that stabilizes blood clots.
Multiple Choice: Which condition is associated with an increased risk of venous thrombosis? A) Prolonged immobility B) Dehydration C) Cancer D) All of the above
D) All of the above
True or False: Hemoglobin F is the main form of hemoglobin present in adult humans.
False
Fill in the blank: The ______ test measures the level of platelets in the blood.
platelet count
What is the condition characterized by excessive bleeding due to a lack of clotting factors?
Hemophilia
Multiple Choice: Which of the following is a common hereditary bleeding disorder? A) von Willebrand disease B) Iron-deficiency anemia C) Sickle cell disease D) Thalassemia
A) von Willebrand disease
What is the primary function of plasma?
To transport blood cells, nutrients, hormones, and waste products.
True or False: Chronic blood loss can lead to iron deficiency.
True
What is the term for a reduced ability to form blood clots?
coagulopathy
Multiple Choice: Which of the following is a common treatment for thrombocytopenia? A) Platelet transfusion B) Iron supplements C) Vitamin K D) All of the above
A) Platelet transfusion
What is the significance of the bone marrow biopsy?
To diagnose hematological disorders and assess bone marrow function.