Hematology Flashcards
Hematopoiesis: Sites of Blood Cell Production
-First trimester: Yolk sac
-Second trimester: Liver, spleen
-Third trimester: Bone marrow
-Birth to 20: Tibia, Femur (Long Bones)
-Age 20: Vertebra, sternum, ribs (Axial Bones)
Erythropoiesis: Process
Myeloid SC>Pro-EB>Basophilic EB>Polychromatic EB>Orthochromatic EB>Reticulocyte>Mature RBC
Types of Hemoglobin
Hb F (alpha 2; gamma 2)-0.5%
Hb A (alpha 2; beta 2)-95-98% (Most Prevalent)
Hb A2 (alpha 2, delta 2)-1.5-2.5%
Lifespan of an RBC
120 days
Hemoglobin: Function
Respiratory protein of RBCs
Hb: Reference Range
Women: 14.0g/dL (+/- 2)
Men: 16.0g/dL
(+/-2)
Hematocrit: Reference Range
Women: 37-47%
Men:
40-54%
Total RBC Count: Reference Range
Women: 3.5-5.5 million/mL
Men
4.3-5.9 million/mL
MCV: Reference Range
80-100fL
Earliest indicator of potential anemia
RDW
RDW: Reference Range
11-15%
WBC count: Reference Range
4,500-11,000/uL
Neutrophils
50-70%
Lymphocytes
20-40%
Monocytes
2-10%