Hematology Flashcards

1
Q

Low ESR

A

PV
Leucocytosis
Sickle cell

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2
Q

JAK2V617F

A

PV
ET
PMF

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3
Q

Microcytic with erythrocytosis

A

Beta thal
Hypoxic erythrocytosis
PV

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4
Q

Drug that shrinks spleen

A

Peg INF alpha

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5
Q

Leucostatic manifestation due to severe leucocytosis or thrombocytosis

A
  1. Vaso occlusive disease
  2. CVA
  3. MI
  4. Venous thrombosis
  5. Priapism
  6. Visual disturbance
  7. Pulmonary insufficiency.
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6
Q

Sokal index

Px in CML

A
Age 
Blasts in circulation 
Count platelet 
Splenomegaly
Cytogenetic abN
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7
Q

M:E increased

A

CML

Leukemoid reaction

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8
Q

M:E decreased

A

Hemolytic anemia

Megaloblastic anemia

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9
Q

Normal M:E ratio in pathology

A

Anaplastic anemia

Myelosclerosis

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10
Q

Conditions where patient may have CRF with enlarge kidney size are:

A

a. Diabetes
b. Polycystic kidney
c. Amyloidosis
d. Multiple Myeloma
e. Bilateral hydronephrosis

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11
Q

POEMS syndrome in MM

A
Osteosclerotic myeloma associated with 
Polyneuropathy 
Organomegaly 
Endocrinopathy 
Monoclonal gammopathy 
Skin changes
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12
Q

MPN with no hepatomegaly, no splenomegaly and no lymph adenopathy.

A

In MM there is no hepatomegaly, no splenomegaly and no lymph adenopathy.
b. CHF is not a feature of MM.

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13
Q

MPN WITH no hepatomegaly, no splenomegaly and no lymph adenopathy.

A

In MM there is no hepatomegaly, no splenomegaly and no lymph adenopathy.
b. CHF is not a feature of MM.

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14
Q

Triad of MM

A
  1. BM plasmacytosis >10% 2. Lytic lesion in the bones in X-ray 3. Urine or plasma M components
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15
Q

Conditions with decreased ESR

A
  1. Polycythemia vera
  2. CHF
  3. Sickle cell anemia
  4. Afibrinogenemia
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16
Q

Conditions with increased ESR that need to be remembered:

A
  1. Multiple myeloma
  2. Anemia other than sickle cell
  3. Giant cell arteritis
  4. De Quervain thyroiditis
17
Q

MGUS Complications

A

i. Solid tumours.
ii. Lymphomas
iii. Amyloidosis
iv. Chronic lymphatic leukemia

18
Q

Triad of hairy cell leukemia

A

a. Massive splenomegaly
b. Pancytopenia
c. Vasculitis
like syndrome i.e. Erythema Nodosum, Cutaneous nodules

19
Q

Subacute cerebellar degeneration

A

a. Small cell carcinoma lung
b. Thymoma
c. Neuroblastoma

20
Q

Causes of MAHA

A

a. HUS
b. TTP
c. Prosthetic Metallic valve
d. Malignant Hypertension