Golden lines 🏆

Question 1

An increased RBC mass, normal plasma volume, and low erythropoietin levels with massive Splenomegaly

Answer 1

PV

Question 2

Tear drop RBC with massive splenomegaly

Answer 2

Myelofibrosis

Question 3

Leukemia patient with bleeding tendency with auer rod, azurophilic granules, t (15:17) translocation responding to vitamin A therapy

Answer 3

M3 AML

Question 4

A child of age 2 to 8 yrs with fever, with high TLC Count, containing Tdt +ve cells

Answer 4

ALL

Question 5

Hillar lymphadenopathy, Reed sternberg cell in histology

Answer 5

Hodgkin lymphoma

Question 6

African patient with, jaw mass, c- myc oncogene, t (8:14) translocation and starry sky appearance in histology

Answer 6

Burkitt

Question 7

Anemia with reticulocytosis

Answer 7

Hemolytic Anemia

Question 8

Reduced free heptoglobin, black color of urine

Answer 8

I/V hemolytic anemia

Question 9

A patient comes with first morning urine sample black & the whole day urine color is normal

Answer 9

PNH

Question 10

In HB electrophoresis:
HBA absent
HBA2 ↑ ↑
HBF ↑ ↑

Answer 10

Beta thalassemia (major)

Question 11

Coomb’s positive Hemolytic Anemia occurring in a patient of SLE, CLL

Answer 11

AIHA

Question 12

In any chronic disease, anemia with

1. Increased Hepcidin and Ferritin
2. Low TIBC and Transferrin saturation is

Answer 12

AOCD

Question 13

A black African male patient coming with sudden onset of intravascular hemolytic anemia, after taking any drug with Heinz body and bite cells in PBF

Answer 13

G6PD deficiency

Question 14

Anemia patient with splenomegaly with pigment gall stones and increased osmotic fragility

Answer 14

HS

Question 15

A patient of anemia on plant diet

Answer 15

vitamin 12 deficiency

Question 16

Elderly anemic patient with optic atrophy & neurological features

Answer 16

Pernicious Anemia

Question 17

The triad of
low hemoglobin,
thrombocytopenia,
and absent hematopoietic cells in the bone marrow is consistent with

Answer 17

Aplastic anemia

Question 18

Extra Vascular hemolytic anemia with ishemic episodes with autosplenectomy

Answer 18

SCA

Question 19

Any black person with unexplained haematuria

Answer 19

screen for SCA

Question 20

Purpura in children occurring 2-3 weeks after viral infection with isolated thrombocytopenia with giant platelet

Answer 20

ITP

Question 21

Patient with bleeding tendency with ________ platelet aggregation in response to Ristocetin is reduced

Answer 21

vWD

Question 22

Any young Caucasian patient below the age of 45, with any venous thrombotic event or in any person with a family history of venous thrombosis

Answer 22

Factor V Leiden

Question 23

In patient that develops recurrent thrombosis while on anticoagulant consider

Answer 23

HIT or cancer related thrombosis (very resistant)