Hematologic Disorders Flashcards

1
Q

How is Anemia Diagnosed

A
  • CBC
  • reticulocyte count
  • peripheral blood smear
  • Hgb: severity
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2
Q

Mild Anemia

A

no symptoms

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3
Q

Moderate anemia

A

palpitations, bounding pulse, roaring ears, fatigue

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4
Q

Severe Anemia

A

skin color changes, eye changes, neuro changes

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5
Q

Aging anemia

A

Hgb can decline, anemia not a normal finding, symptoms are not specific finding, symptoms are not specific

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6
Q

Anemia Geriatric

A
  • more common in the 70s

- may be mistaken for normal aging

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7
Q

most susceptible for iron-deficiency anemia

A
  • Very young
  • Poor diet
  • Women in reproductive years
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8
Q

ID Anemia Care

A
  • nutrition
  • iron supplements
  • packed RBCs
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9
Q

Thalassemia

A
  • A group of diseases involving inadequate production of normal Hgb
  • Results in decreased erythrocyte production
  • pale or jaundice, splenomegaly, bone marrow hyperplasia
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10
Q

Thalassemia Care

A
  • blood transfusion

- splenectomy

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11
Q

Megaloblastic anemias

A
  • cobalamin (B12) & folic acid deficiency
  • sore, beefy, red, tongue
  • weakness of hands & ft
  • antaxia
  • confusion
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12
Q

MB Anemia Care

A
  • IV or intranasal cobalamin

- normal folate (3-16) replaced

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13
Q

what differentiates folic acid deficiency from B12?

A

folic acid lack neuro problems

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14
Q

Aplastic Anemia

A

pancytopenia: decrease in all blood cell types

- immune therapies & bone marrow transplantation

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15
Q

Acute blood loss

A

sudden hemorrhage

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16
Q

Chronic blood loss sources

A
  • bleeding ulcer
  • hemorrhoids
  • menstrual & postmenopausal blood loss
17
Q

Acquired Hemolytic Anemia

A

Results from hemolysis of RBCs from extrinsic factors
•Physical destruction
•Antibody reactions
•Infectious agents and toxins

18
Q

Hemochromatosis

A
  • iron overload disorder

- genetic link

19
Q

Thrombocytopenia

A
  • avoid aspirin
  • fever, lethargy, bleeding, abdomen distention, splenomegaly
  • platelet transfusions & blood component therapy
20
Q

AML Leukemia

A

uncontrolled proliferation of myeloblasts

21
Q

ALL leukemia

A

immature small lymphocytes proliferate in bone marrow

22
Q

CML leukemia

A

excessive mature neoplastic granulocytes move into liver & spleen

23
Q

CLL leukemia

A

accumulation of inactive lymphocytes infiltrate the bone marrow, spleen, & liver

24
Q

Leukemia signs

A
  • fever, lymphadenopathy, lethargy

- pallor, jaundice, petechiae, ecchymoses

25
Q

Leukemia Diagnostics

A
  • low Hct &Hgb
  • anemia
  • thrombocytopenia
  • Philadelphia chromosome
26
Q

Hodgkin’s Lymphoma signs

A
  • enlargement of lymph nodes
  • mediastinal mass
  • weight loss, fatigue, weakness, fever
  • late: spleno/hepatomegaly
  • A&B and roman numeral class
27
Q

Non-Hodgkin’s

A
  • manage probs related to disease
  • decrease platelets
  • at risk for spontaneous bleeding