Hematologic Disorders Flashcards
What are sickle cell anemia individuals predisposed to?
Salmonella osteomyelitis
What is a radiographic feature of the spine of Sickle Cell Anemia?
Fish/H-vertebra
What kind of weather aggravates the patient with Sickle Cell Anemia?
Cold weather
What is the preferred method for evaluation of imaging for Sickle Cell Anemia?
MRI
What is the most sensitive study for Sickle Cell Anemia?
T1 fat saturation post gadolinium contrast
In Sickle Cell Anemia patients, What is the name of repeated episodes of splenic infarction causing the spleen to decrease in size?
Autosplenectomy
What is a common finding in individuals with Sickle Cell Anemia?
Dactylitis
What is a key radiographic finding of the skull with Sickle Cell Anemia and Thalassemia?
Hair-on-end appearance
What condition has most of the following:
- retarded growth
- hepatosplenomegaly
- Mongoloid facies
- maxillary overgrowth
- inhibited sexual development
Thalassemia
What are some complications of Thalassemia?
repeated transfusions results in hemochromatosis (due to iron overload) and subsequent cardiac failure
What are the key radiographic findings of Thalassemia?
Erlenmeyer Flask Deformity
Honeycomb trabeculae
Hyperplasia of bone marrow
What are the 2 most common bleeding disorders with skeletal abnormalities that are from repeated intraarticular bleeding?
Classic Hemophilia (hemophilia A) Christmas Disease (hemophilia B)
Who usually manifests hemophilia?
males
How do skeletal changes come about in individuals with Hemophilia?
from hemorrhages within or around joints and bones
Where is a pseudotumor the most common site for Hemophilia?
ilium and femur
