Hematologic Diseases Flashcards

1
Q

What is the most common hemolytic anemia?

A

Sickle cell anemia

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2
Q

What is the race bias associated with sickle cell anemia?

A

African Americans

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3
Q

What is another name for sickle cell anemia and why?

A

“Hands and feet syndrome” - patients present with pain and swelling in the hands and feet

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4
Q

How can sickle cell affect the patient’s GI tract?

A

Infarct of bowel following obstruction of the mesenteric arteries (abdominal crisis)

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5
Q

Sickle cell presents with a predisposition for what kind of bone infection?

A

SALMONELLA osteomyelitis (remember the most common is usually Staph aureus, so this is super unique)

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6
Q

What are some of the radiographic features seen with sickle cell?

A

Marrow hyperplasia, hair on end skull, Erlenmeyer flask, H shaped vertebra

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7
Q

What are other names for the H shaped vertebrae seen with sickle cell?

A

Lincoln Log vertebrae, Reynold’s phenomenon

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8
Q

What is another name for thalassemia?

A

Cooley’s anemia

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9
Q

What ethnicity is more likely to get thalassemia?

A

Those of Mediterranean origin

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10
Q

What are the forms of thalassemia?

A

Minor, intermedia, major

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11
Q

What is the patient presentation for thalassemia?

A

Fatigue due to chronic anemia, splenomegaly, cardiomegaly, gallstones

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12
Q

What are the features of thalassemia?

A

Marrow hyperplasia, extra medullary hematopoiesis, maxillary overgrown (aka rodent facies), hair on end skull

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13
Q

Which radiographic feature is ultra sensitive to sickle cell?

A

Lincoln log vertebra

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14
Q

Which feature is ultra sensitive to thalassemia?

A

Hair on end skull (also rodent facies)

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15
Q

Honeycomb coarsened trabeculation is seen with what condition?

A

Thalassemia

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16
Q

Hair on end skull is more likely to be seen with what blood condition?

A

Thalassemia

17
Q

What is hemophilia?

A

Inability to clot (X-linked disease carried by females and manifested in males)

18
Q

What causes the juxta-articular osteoporosis seen with hemophilia?

A

Hyperemia

19
Q

What is the major radiographic sign seen with Leukemia?

A

Radiolucent submetaphyseal bands (also growth arrest lines)