AVN Flashcards
What part of a long bone is likely to be affected by AVN?
Epiphysis (try to remember that suppurative infection SPARES the epiphysis)
What specific bone of the bone is more likely to develop AVN?
Femur head and humeral head
What are some synonyms for AVN?
Osteonecrosis, ischemic necrosis, osteochondrosis
When does epiphyseal necrosis become clinically evident?
With articular surface collapse
What is the clinical latent period of AVN?
Weeks to a year
What is the most common etiology category for AVN?
Spontaneous/idiopathic (others include surgery, trauma, alcoholism, corticosteroid usage)
What causes AVN?
Obstruction of extra- and intraosseous vessels by arterial embolism, venous thrombosis, traumatic disruption, or external compression
What is the time frame from initial infarction to healed deformity for AVN?
2-8 years
What causes of AVN fall under the etiology category of external vessel compression?
Trauma, steroids, infection, gaucher’s disease, hyperlipidemia
What causes of AVN fall under the etiology category of vessel wall disorders?
RA, LE, radiation, polyarteritis nodosa
What causes of AVN fall under the etiology category of thrombo-embolic disorders?
Alcoholism, steroid, trauma, sickle-cell, caisson’s
What is caisson’s disease?
Decompression sickness
What are the four stages of AVN?
Avascular, revascularization, repair, deformity
What happens in the avascular stage of AVN?
Obliteration of epiphyseal blood supply, altered growth, altered cartilaginous growth
The altered cartilage seen with AVN can lead to what further condition?
DJD
Most X-ray findings of AVN are seen during which stage?
Revascularization
What is the term for when deposition occurs and new bone is deposited directly on dead bone therefore thickening the trabeculation and increasing bone density with AVN during the revascularization phase?
Creeping substitution
What is the radiographic sign that is definitive for AVN?
Crescent sign
What is the best procedure of choice to diagnose AVN?
MRI
During which phase of AVN can we see the mushroom deformity and sagging rope sign?
Repair/remodeling phase
What is the major factor in residual deformity following AVN?
How much compressive force is exerted on the necrotic bone during revascularization and repair phases
What is the trabecular pattern seen with AVN?
Mottled appearance: thickened irregular pattern traversing the necrotic areas usually in revascularization and repair phases
What is the name of the condition of AVN in the adult femoral head?
Chandler’s disease
What is most likely the condition at hand with BILATERAL C-shaped lesions all over the distal femur and proximal tibia?
Metaphyseal/diaphyseal infarcts from AVN
What is the gender and age bias for Chandler’s disease?
Males ages 30-70
What is the radiographic sign of a necrotic area that tends to be wedged or semilunar shaped with a central apex seen in Chandler’s disease?
“Bite sign”