HEMA LEC (OVERVIEW) Flashcards

1
Q

Red blood cell (RBC) also called

A

erythrocyte

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2
Q

White blood cell (WBC) or ___

A

leukocyte

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3
Q

Platelet or ___

A

thrombocyte

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4
Q
  • Study of blood cells
A

Hematology

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5
Q

Red blood cells are (ABDC)

A

Anucleate, biconcave, discoid cells

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6
Q

Size of RBC

A

6 to 8 um

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7
Q

it is Filled with ____, ____

A

reddish protein,
Hemoglobin (Hgb)

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8
Q

transports
oxygen (O2) and carbon
dioxide (CO2)

A

Hemoglobin

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9
Q

Normal RBC count for male

A

4.20 - 6.0 x106/uL

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10
Q

Normal RBC count for female:

A

3.80 - 5.20 x106/uL

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11
Q

RBC count to detect ____ or ____

A

anemia or
polycythemia

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12
Q

loss of
_____ ;
reflected in reduced RBC
count or decreased
hemoglobin concentration

A

Anemia, O2-carrying capacity

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13
Q

increased
RBC count; results to
_____

A

Polycythemia, hyperviscosity

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14
Q

Tiny aliquot of whole blood
mixed with _____

A

0.85% normal
saline

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15
Q

What is the desired dilution for RBC?

A

1:100 or 1:200

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16
Q

what is the material used for the dilution?

A

glass pipette
(Thoma pipette)

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17
Q

the equipment used
to count RBC and that will be focused
manually in the microscope

A

*Hemocytometer

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18
Q

Diluted blood is transferred to glass
counting chamber called

A

hemacytometer

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19
Q

In ___, first electronic counter
patented by ____; called ___

A

1953, Joseph and Wallace
Coulter; called Coulter counters

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20
Q

Whole blood is mixed with ___

A

Drabkin reagent

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21
Q

weak solution
of potassium cyanide and
potassium ferricyanide

A

Drabkin reagent

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22
Q

Hemoglobin is converted to ___

A

cyanmethemoglobin
(hemiglobincyanide);

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23
Q

Hemoglobin measurement for Male

A

13.5 - 18.0 g/dL

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24
Q

Hemoglobin measurement for female

A

12.0 - 15.0 g/dL

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25
Q

ratio of the volume of
packed RBCs to volume of
whole blood

A

Hematocrit

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26
Q

Hematocrit is a ____

A

simply packed cell
volume

27
Q

Hematocrit percentage for male

A

40 - 54 %

28
Q

Hematocrit percentage for female

A

35 - 49 %

29
Q

Reticulocytes aka

A

polychromatic
(polychromatophilic)
erythrocytes

30
Q

Reticulocyte is Newly released from ___

A

bone
marrow (RBC production site)

31
Q

What dyes are used to diff. young RBC

A

Methylene blue dyes (nucleic
acid stains or vital stains)

32
Q

WHITE BLOOD CELLS (WBCS) aka

A

leukocytes

33
Q

Function of WBC

A

Protect host from infection

34
Q

Dilution for WBC

A

1:20

35
Q

Diluent for WBC

A

dilute acid
solution (to lyse RBCs)

36
Q

Leukpenia

A

below
4500/uL

37
Q

Leukocytosis

A

more than
11,500/uL

38
Q

Types of WBC that is Segmented,
polymorphonuclear
neutrophils/ PMNs

A

Neutrophils (NEUTs)

39
Q

engulf
and destroy
microorganisms

A

Phagocytic cells

40
Q

Neutrophilia means

A

(increased
neutrophils) = bacterial
infection

41
Q

Neutropenia means

A

(decreased
neutrophils) = viral
infections or certain
medications

42
Q

bands are

A

Less mature (less
differentiated) neutrophil

43
Q

shape of bands

A

Sausage-shaped or Horseshoe-shaped
(nucleus)

44
Q

Increased bands means

A

bacterial
infection

45
Q

Eosinophils are cells with ___

A

bright orange-red
cytoplasmic granules

46
Q

Eosinophilia

A

(increased
EOs) = allergy or parasitic
infection

47
Q

Color of Eosinophil

A

(reddish granules)

48
Q

Color of Neutrophil

A

(bluish granules)

49
Q

basophils have cells with

A

dark purple
cytoplasmic granules that
obscure the nucleus

50
Q

the granules of Basophils contains

A

histamines

51
Q

Basophilia

A

(increased
BASOs) = rare; signals
hematologic disease

52
Q

high basophil leads to

A

chronic
inflammation

53
Q

Lymphocytes can

A

Recognize foreign antigens
and mount humoral and
cell-mediated responses

54
Q

Lymphocytes is ___

A

Nearly round, slightly larger
than RBCs, round nucleus
and thin rim of cytoplasm

55
Q

Lymphocytosis

A

(increased
LYMPHs) = viral infection

56
Q

Lymphopenia/Lymphocytop
enia

A

(decreased LYMPHs)
= drug therapy or
immunodeficiency

57
Q

prevalent
in people older than 65 y.o

A

Chronic lymphocytic

58
Q

childhood
leukemia

A

Acute lymphoblastic
leukemia

59
Q

Monocytes (MONOs) are

A

Immature macrophage

60
Q

Monocytes (MONOs) is the same with

A

Large WBC

61
Q

color of cytoplasm in monocytes

A

Blue-gray cytoplasm

62
Q

nucleus of mono and shape

A

Indented/folded nucleus
(kidney bean shape)

63
Q

platelets aka

A

thrombocytes