Hema-Erythropoiesis & RBC maturation Flashcards

1
Q

N:C ratio is highly dependent on ____

A

nuclear size

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2
Q

High N:C ratio

A

> 50% of the cell is occupied by the nucleus

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3
Q

Low N:C ratio

A

<50% of the cell is occupied by the nucleus

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4
Q

more RNA

A

Basophilia

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5
Q

Due to acidic components

A

Basophilia

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6
Q

due to basic components

A

Acidophilia

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7
Q

more hemoglobin

A

Acidophilia

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8
Q

N:C ratio 8:1

A

Rubriblast

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9
Q

“wheel spoke”

A

Prorubricyte /
Basophilic normoblast /
basophilic erythroblast

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10
Q

aka EARLY

A

Rubriblast / Pronormoblast / Proerythroblast

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11
Q

aka INTERMEDIATE

A

Rubricyte / Polychromatophilic normoblast / Polychromatophilic erythroblast

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12
Q

the enveloped, excruded nucleus is called a

A

Pyrenocyte

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13
Q

aka LATE

A

Metarubricyte / Orthochromic normoblast / Orthochromic erythroblast

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14
Q

N:C ratio 4:1

A

Rubricyte / Polychromatophilic normoblast / Polychromatophilic erythroblast

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15
Q

Muddy Gray Cytoplasm

A

Rubricyte / Polychromatophilic normoblast / Polychromatophilic erythroblast

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16
Q

Salmon Pink cytoplasm

A

Metarubricyte / Orthochromic normoblast / Orthochromic erythroblast

17
Q

has Residual RNA

A

Reticulocyte

18
Q

last stage with nucleus

A

Metarubricyte / Orthochromic normoblast / Orthochromic erythroblast

19
Q

last stage of hemoglobinization

A

Reticulocyte

20
Q

Reticulocyte other names

A

Polychromatophilic erythrocyte / Diffusely Basophilic erythrocyte

21
Q

Dense, Pyknotic nucelus

A

Metarubricyte / Orthochromic normoblast / Orthochromic erythroblast

22
Q

lifespan of Reticulocyte in the circulation

A

1 day

23
Q

Erythrocyte is aka

A

Mature RBC

24
Q

Mature RBC thickness

A

1.5-2.5 um

25
Q

lifespan of Mature RBC

A

120 days

26
Q

Eccentric nucleus

A

Rubricyte / Polychromatophilic normoblast / Polychromatophilic erythroblast

27
Q

Checkerboard appearance

A

Rubricyte / Polychromatophilic normoblast / Polychromatophilic erythroblast

28
Q

also called nucleated RBC & Acidophilic normoblast

A

Metarubricyte / Orthochromic normoblast / Orthochromic erythroblast

29
Q

N:C ratio for Metarubricyte

A

2:1

30
Q

more apparent hemoglobin synthesis

A

Rubricyte / Polychromatophilic normoblast / Polychromatophilic erythroblast

31
Q

N:C ratio of Prorubricyte

A

6:1

32
Q

earliest recognizable precursor

A

Prorubricyte

33
Q

last stage with nucleolus then later disappears in this stage

A

Prorubricyte